Anti-Obesity Drug Use before Professional Treatment in Taiwan

臺灣民眾尋求專業減肥前使用減肥藥物情況之調查

Tsan-Hon Liou ； Chih-Hsing Wu ； Hsu-Chen Chien ； Wen-Yuan Lin ； Wei-Jei Lee ； Pesus Chou

《Asia Pacific Journal of Clinical Nutrition》 16卷3期 (2007/09) Pp. 580-586

https://doi.org/10.6133/apjcn.2007.16.3.25

摘要

本研究於西元2004年7月到2005年6月進行一項橫斷式調查，希望瞭解臺灣民眾在尋求專業減肥之前使用減肥藥物的情形，經由隨機分層抽樣的方法，選取十八家專業減肥醫院或診所，並由這些門診挑選18歲以上的受訪者共1,060位，其中女性791位、男性269位，每位受訪者皆填寫完成一份問卷。統計發現這些受訪者使用減肥藥物的盛行率是50.8%，其中女性高於男性（53.6%比42.4%）。1,060位受訪者中，17.1%曾經使用過orlistat、21.1%使用過sibutramine、18.3%使用過雞尾酒減肥療法或未經證實的減肥藥，此外23.6%受訪者指出在減肥期間合併使用中藥減肥、22.4%合併補充減肥健康食品。邏輯式迴歸分析發現，女性、年齡介於18－24歲、身體質量指數（BMI）大於35、同時合併使用減肥中藥／健康食品的受訪者使用減肥藥物的機會較高。總而言之，臺灣成年民眾在尋求專業減肥之前，使用減肥藥物的情形相當普遍，尤其是女性、超重和那些同時合併使用中藥及健康食品減肥的民眾；此外，相關單位對於未經證實的減肥藥物使用情形必須進一步了解。

關鍵字

健康食品 ； 禁藥 ； 藥物使用

並列摘要

Between July 2004 and June 2005, a cross-sectional study was performed to determine the prevalence and patterns of anti-obesity medicine use among subjects seeking obesity treatment in Taiwan. Eighteen obesity outpatient clinics were selected via a random stratified sampling method and 1,060 first-visit clients (791 females and 269 males) aged above 18 years were enrolled and then completed a self-administered questionnaire. The prevalence of anti-obesity medicine use was 50.8%; more females than male used anti-obesity medicines (53.6% vs. 42.4%). Of the 1,060 subjects, 17.1% had used orlistat, 21.1% had taken sibutramine, and 18.3% had utilized unproven drugs such as cocktail therapy and other anti-obesity drugs. Furthermore, 23.6% and 22.4% of subjects indicated that they concurrently used Chinese herbal preparations and dietary supplements, respectively. Logistic regression analyses demonstrated that the odds ratio (OR) for anti-obesity medicine use was substantially higher in females (OR, 1.9; 95% CI, 1.3-2.6), those aged 18-24 years (OR, 1.6; 95% CI, 1.0-2.6), those with a body mass index (BMI) ＞35 kg/m^2 (OR, 3.4; 95% CI, 2.1-5.7) and respondents concurrently using Chinese herbal preparations (OR, 1.7; 95% CI, 1.2-2.4) and dietary supplements (OR, 2.2; 95% CI, 1.6-3.1). In conclusion, the prevalence of anti-obesity drugs use is high among Taiwanese adults before they seek obesity treatment. Young, obese females, and those who had taken Chinese herbal preparations/dietary supplements had a high likelihood to report using anti-obesity medicines. Use of unproven weight-loss drugs is common and warrants further investigation.

並列關鍵字

Orlistat ； sibutramine ； dietary supplement ； off-label drugs ； drug utilization