市售高鈣高鐵奶粉之鐵質生體可用率

Bioavailability of Iron from Commercial Milk Powder Fortified with Both Calcium and Iron

張美鈴(Mei-Ling Chang) ； 彭珍芳(Jen-Fang Perng) ； 蕭寧馨(Ning-Sing Shaw)

《中華民國營養學會雜誌》 23卷3期 (1998/08) Pp. 251-264

https://doi.org/10.6691/JCNS.199808_23(3).0004

摘要

爲了解市售高鈣高鐵奶粉的鐵營養價值，本研究利用貧血大鼠血紅素再生法測定其鐵質相對生物價，其中包括兩個實驗：實驗一評估奶粉A的鐵生體可用率，實驗二比較奶粉A與奶粉B的鐵可用率。奶粉A爲知名的高鈣高鐵奶粉，奶粉B爲加鐵強化奶粉，於1998年2月購自北市的超市。實驗一採用雄性離乳Wistar大鼠，經耗鐵貧血後，分爲十三組，分別飼以標准飼料（以FeSO4供鐵0ppm，6ppm，12ppm，18ppm，35ppm）；奶粉飼料（以奶粉A提供鐵6ppm，12ppm，18ppm）；奶粉A對飼育組（每天供應2g，3g，4g，6g奶粉A）；和奶粉B對飼育組（每天供應3公克奶粉B）；兩週的血紅素再生期後，奶粉A與其對飼育組的血紅素再生率(19%～29%)顯著低於標准飼料(69%～90%)和奶粉B(79%)。實驗二利用奶粉A與對飼育組的貧血大鼠24隻，分四組各飼以標准飼料（FeSO4供鐵18ppm），奶粉A飼料（奶粉A供鐵24ppm與36ppm），奶粉B飼料（奶粉B供鐵24ppm），經再生期十天，測得血紅素再生率以奶粉A顯著低於硫酸亞鐵與奶粉B。奶粉A的鐵質相對生物價爲26，奶粉B爲75.5，可見市售高鈣高鐵奶粉之鐵質相對生物價偏低，以所用鐵化合物之生體可用率偏低之爲主因。

關鍵字

鐵生體可用率 ； 鐵相對生物價 ； 血紅素再生率 ； 高鈣高鐵奶粉

並列摘要

Relative biological values of Iron from of commercial milk powder fortified with both calcium and iron were measured using a rat hemoglobin regeneration bioassay. Two sets of experiments were carried out, iron bioavailability of milk powder brand A was measured in experiment one, and iron bioavailability of two brands of milk powder, A and B, was evaluated in experiment two. Milk powder A is fortified with both Ca and Fe, milk powder B is fortified with Fe, and both were purchased from supermarket in Taipei in February, 1998. In experiment one, male weanling Wistar rats were divided into 13 groups after being anemic; in hemoglobin repletion period, 5 groups were fed on standard diets (FeSO4 provided 0ppm, 6ppm, 12ppm, 18ppm and 35ppm of Fe), 3 groups were fed on milk A diets (milk A provided 6ppm, 12ppm, and 18ppm of Fe), 4 groups were pair-fed on milk A (daily supply of 2g, 3g, 4g and 6g of milk A powder), and one group was pair-fed on milk B (daily supply of 3g of milk B powder). The hemoglobin regeneration efficiency of milk A (19%-29%) was significantly lower than that of FeSO4 (69%-90%) and that of milk B (79%). Twenty four anemic rats from experiment one were used for experiment two. They were divided into 4 groups, and one group fed on standard diet (18ppm Fe from FeSO4), two groups fed on milk A diets (24ppm and 36ppm Fe from milk A), and one group fed on milk B diet (24ppm Fe from milk B). After ten days of hemoglobin repletion, the hemoglobin regeneration efficiency of milk A was significantly lower than that of both FeSO4 and milk B. The relative biological value of iron was 26 for milk A and 75.5 for milk B. The low relative biological value of iron from commercial milk powder fortified with both Ca and Fe was mainly due to the the low bioavailability of iron compounds used for fortification.

並列關鍵字

iron bioavailability ； relative biological value of iron ； hemoglobin regeneration efficiency ； Ca- and Fe- fortified milk powder