Unilateral Sinonasal Disease

背景：本研究旨在探討在臺灣單一醫院5年來單側鼻腔鼻竇疾病接受治療病患的臨床症狀、放射學發現、病理組織及微生物培養上的結果。方法：我們以回溯性方式自2007年1月到2011年12月的病歷紀錄中，收集經由電腦斷層診斷爲單側鼻竇病變且接受鼻竇內視鏡手術的病人，針對性別、年齡、臨床症狀、電腦斷層上的發現、病理組織及微生物培養的結果做分析。結果：此研究病人人數總計有103名（67名男性，36名女性，年齡分佈在17歲至80歲之間，平均年齡為40.9 ± 18.3歲），鼻塞和鼻漏為最常見的臨床症狀，性別分佈男性多於女性，上頜竇為最好發的電腦斷層之單側鼻竇病變，其次為竇口鼻道複合體、篩竇、額竇及蝶竇，依據病理組織上的發現，病人當中有68.9%為慢性鼻竇炎、9.7%為黴菌性鼻竇炎，21.4%為良性或惡性腫瘤，慢性鼻竇炎最常見的致病菌為葡萄球菌而黴菌性鼻竇炎則是麴菌屬。結論：慢性細菌性鼻竇炎是單側鼻腔鼻竇疾病中最常見的疾病，且從電腦斷層影像中，上頜竇為最好發的病灶，即便如此，黴菌性鼻竇炎、良性及惡性腫瘤仍應列入單側鼻竇疾病病人的鑑別診斷當中。

關鍵字

單側鼻腔鼻竇疾病；鼻竇內視鏡手術；慢性鼻竇炎；黴菌性鼻竇炎

並列摘要

BACKGROUND: The aim of this study was to describe the clinical features, radiological findings, histopathology and microbiology of unilateral sinonasal disease treated at a single institution in Taiwan over a period of five years.METHODS: The medical records of patients with unilateral sinonasal opacification on computed tomography (CT) that received endoscopic sinus surgery between January 2007 and December 2011 were retrospectively analyzed. The patients' age, gender, clinical symptoms, CT findings, histopathology, and microbiology results were collected for further analysis.RESULTS: A total of 103 patients (67 males and 36 females ranging from 17 to 80 years of age, mean age 40.9 ± 18.3 years) were enrolled in this study. Nasal obstruction and rhinorrhea were the most common symptoms. There were more males than females. The CT results most commonly showed unilateral sinonasal opacification in the maxillary sinus followed by the ostiomeatal complex, ethmoid, frontal and sphenoid sinuses. Based on the histopathology findings, about 68.9% of the patients had chronic rhino-sinusitis, 9.7% had fungal sinusitis, and 21.4% had benign or malignant tumors. Staphylococcus was the most common pathogen associated with chronic rhino-sinusitis and Aspergillus was the most common pathogen associated with fungal sinusitis.CONCLUSIONS: Chronic bacterial rhino-sinusitis was the most frequent final diagnosis in the patients with unilateral sinonasal disease and the maxillary sinus was the most common sinus affected. Fungal sinusitis and tumors should always be included in the differential diagnosis of unilateral sinonasal disease.

並列關鍵字

unilateral sinonasal disease ； endoscopic sinus surgery ； chronic rhinosinusistis ； fungal sinusitis

國際替代計量

Unilateral Sinonasal Disease

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