Allergic Contact Dermatitis of Paraphenylenediamine

對次酚二胺過敏性接觸皮膚炎

王綺嫻(Chii-Shyan Wang) ； 曾美萍(Mei-Ping Tseng) ； 孫啟璟(Chee-Ching Sun)

《中華皮膚科醫學雜誌》 19卷3期 (2001/09) Pp. 184-189

https://doi.org/10.29784/DS.200109.0001

摘要

對次酚二胺(para-phenylenediamine,PPD)是染髮劑中廣為使用之中間物質，而且是非常強的過敏原，常造成美髮師的過敏性接觸皮膚炎。我們報告二十二年來在臺大醫院對於PPD之貼膚試驗的結果。在3322位受試者當中，有115位(3.46%)對PPD呈現過敏反應。PPD所造成的皮膚炎，最常見的位置為臉部(41.5%)及手部(28.3%)。PPD造成的過敏性接觸皮膚炎在美髮業者最常見的位置為手部，在非美髮業者為臉部。美髮業者對PPD過敏的危險性高於非美髮業者(ood ratio=20.4)。我們並針對PPD過敏緎接觸皮膚炎作整理回顧。

並列摘要

Para-phenylenediamine (PPD), a primary intermediate in hair dye, is a potent contact allergen and a common cause of allergic contact dermatitis in hairdressers. We report the results of patch testing with PPD in National Taiwan University Hospital in the past 22years. 115(3.46%) of the total patch-tested 3322patients were positive to PPD. The commonest sites of dermatitis were the face (41.5%) and the hand (28.3%). Hands of hairdressers and face of non-hairdressers were the commonest site of allergic dermatitis of PPD. Hairdressers had an increased risk to be allergic to PPD (odds ratio=20.4). We also review the literatures about allergic contact dermatitis to PPD.

並列關鍵字

Contact dermatitis ； Patch test ； Para-phenylenediamine