兒童與青少年代謝症候群

Metabolic Syndrome in Children and Adolescents

蔡孟書(Meng-Shu Tsai) ； 周致暄(Chih-Hsuan Chou) ； 吳英黛(Ying-Tai Wu)

《物理治療》 37卷2期 (2012/06) Pp. 104-113

摘要

本文簡介兒童與青少年代謝症候群的機制、診斷標準、預防和介入。代謝症候群是指含肥胖及血脂異常、血糖代謝異常及高血壓相關共病症的集合症狀，與糖尿病及心血管疾病密切相關。受種族、年齡及發展的影響，至今全球對兒童及青少年代謝症候群仍無一致的診斷標準。胎兒時期的母體子宮環境、懷孕母體營養過多或不足、兒童及青少年的過度營養及身體活動量下降都是造成代謝症候群的重要因素。學者建議改變生活型態、減重來控制代謝症候群的危險因子，加以預防及治療。目前研究顯示生活型態介入對代謝症候群有良好效果，唯仍缺乏較高證據等級之隨機控制研究的支持。

關鍵字

代謝症候群 ； 兒童 ； 青少年

並列摘要

The purpose of this review was to discuss the mechanism, diagnostic criteria, prevention, and clinical intervention for children and adolescents with metabolic syndrome. Metabolic syndrome is a group of risk factors which closely related to cardiovascular diseases and diabetes mellitus. Obesity, dyslipidemia, impaired glucose metabolism, and elevated blood pressure constitute the components of metabolic syndrome. Ethnicity as well as age and developmental processes have influential effects on metabolic risk factors. There is no consensus on the diagnostic criteria with worldwide acceptance for metabolic syndrome among this population. The environment for uterine fetal development, over-or under-nourishment of the pregnant mother, and over-nutrition and/or decreased physical activity in childhood may lead to the metabolic syndrome in children. Lifestyle intervention, weight loss and reduction of metabolic risk factors are recommended as prevention measures and as the main treatment goal for children and adolescents with metabolic syndrome. Although lifestyle intervention has been shown to have beneficial effects in several clinical trials, more well-designed randomized controlled trials are required in the future.

並列關鍵字

Metabolic syndrome ； Children ； Adolescents