本省產櫻蝦對大白鼠血漿及肝臟膽固醇含量之影響

Effect of Sakura Shrimp (Sergia lucens Hansen) on Plasma and Liver Cholesterol Levels in Rats

姚賢宗(Hsien-Tsung Yao) ； 蔡慧君(Huey-Jine Chai) ； 吳純衡(Chwen-Herng Wu) ； 江孟燦(Meng-Tsan Chiang)

《臺灣農業化學與食品科學》 42卷4期 (2004/08) Pp. 259-265

https://doi.org/10.6578/TJACFS.2004.034

摘要

本研究係探討本省產櫻蝦對大白鼠血漿及肝臟膽固醇含量的影響。試驗分為二組，分別是控制組及櫻蝦組，飼料中含有10%豬油及0.5%膽固醇，試驗共進行四週。結果發現，大白鼠攝食櫻蝦後會明體降低血漿總膽固醇、極低密度脂蛋白膽固醇並提高高密度脂蛋白膽固醇/總膽固醇比值。此外，攝食櫻蝦後會明顯降低肝臟膽固醇含量，但不改變糞便膽固醇及總膽酸含量。大白鼠攝食櫻蝦後，血漿游離胺基酸中除了taurine濃度顯著增加外，其他游離胺基酸濃度並無明顯改變。綜合以上的結果顯示，櫻蝦會明顯降低大白鼠血漿及肝臟膽固醇含量，其原因可能與血漿taurine濃度增加有關。

關鍵字

櫻蝦 ； 膽固醇 ； 大白鼠

並列摘要

To investigate the effect of sakura shrimp (Sergia lucens Hansen) on plasma and liver cholesterol levels, male Sprague-Dawley rats fed a high fat (10% lard) and cholesterol-riched (0.5%) diet were studied for four weeds. Rats were divided into two groups: control group and sakura shrimp group. Lower plasma total cholesterol (TC) and very low-density lipoprotein cholesterol (VLDL-C) concentration, and higher ratio of plasma high-density lipoprotein cholesterol (HDL-C) to total cholesterol were observed in rats fed with the sakura shrimp diet when compared with those fed with the control diet. In addition, rats fed with the sakura shrimp diet had decreased liver cholesterol contents. No significant difference in fecal cholesterol and total bile acid excretion was observed between the two dietary groups. The concentration of plasma taurine was significantly increased in sakura shrimp group. Results from this study suggest that sakura shrimp may induce a reduction in plasma and liver cholesterol levels in rats, which might be related to the increased plasma taurine concentration.

並列關鍵字

Sakura shrimp(Sergia lucens Hansen) ； Cholesterol ； Rats