- 期刊
Intensity-modulated Radiation Therapy is an Effective Treatment for Optic Nerve Sheath Meningioma
並列摘要
A 39-year-old woman presented to our clinic with a two-week history of blurred vision in the right eye. Best corrected visual acuity was 20/25 in the right eye (RE) and 30/20 in the left eye (LE). Visual field (VF) test revealed an inferior altitudinal defect in the RE. Magnetic resonance imaging (MRI) of brain and orbit demonstrated an enlarged right intraorbital optic nerve sheath complex measuring 2 cm in length and 7 mm in diameter with prominent enhancement, findings consistent with optic nerve sheath meningioma (ONSM). The patient underwent intensity-modulated radiation therapy (IMRT), receiving a total dose of 54 Gy in 30 fractions over a period of 42 days. At fourmonth follow-up, visual acuity in the RE was 20/20 and the altitudinal defect had resolved. At 30- month follow-up, serial VF showed progressive resolution of scotoma. IMRT provided effective treatment for ONSM in our patient; however, long-term monitoring is warranted.
延伸閱讀
- Kao, W. H., Hong, J. H., Chao, A. N., & Wang, C. C. (2014). Fractionated Stereotactic Radiotherapy for Choroidal Melanoma. 放射治療與腫瘤學, 21(3), 191-199. https://doi.org/10.6316/TRO/201421(3)191
- Lin, Y. H., Yen, S. H., Tsai, C. C., Kao, S. C., & Lee, S. M. (2012). Treatment of Refractory Bilateral Idiopathic Orbital Inflammation with Adjunctive Radiotherapy. 中華民國眼科醫學會雜誌, 51(1), 90-94. https://doi.org/10.30048/ACTASOS.201203.0013
- Wang, Y. J., Hsu, F. M., Chen, Y. H., Tsai, C. L., Chen, W. Y., Cheng, J. C. H., & Kuo, S. H. (2014). Radiotherapy for Intracranial Germinoma: Treatment Modalities and Clinical Outcome. 放射治療與腫瘤學, 21(2), 111-119. https://doi.org/10.6316/TRO/201421(2)111
- Fan, N. W., Wang, A. G., & Yen, M. Y. (2011). Compressive Optic Neuropathy in a Patient with Provisional Diagnosis of Huge Meningioma-A Case Report. 中華民國眼科醫學會雜誌, 50(1), 199-204. https://doi.org/10.30048/ACTASOS.201104.0030
- Jabbour, S. K., Patel, S., Herman, J. M., Wild, A., Nagda, S. N., Altoos, T., Tunceroglu, A., Azad, N., Gearheart, S., A.Moss, R., Poplin, E., Levinson, L. L., Chandra, R. A., Moore, D. F., Chen, C., Haffty, B. G., & Tuli, R. (2012). Intensity-Modulated Radiation Therapy for Rectal Carcinoma Can Reduce Treatment Breaks and Emergency Department Visits. International Journal of Surgical Oncology, 2012(), 488-494. https://doi.org/10.1155/2012/891067