Suspected Oral, Mesentric and Cutaneous Metastasis of Uveal Melanoma in a Dog: A Case Report

犬眼睛葡萄膜黑色素瘤疑似轉移至口腔、腸繫膜與皮膚之病例報告

駱虹霏(Hung-Fei Lo) ； 劉振軒(Chen-Hsuan Liu) ； 葉力森(Lih-Seng Yeh) ； 蘇璧伶(Bi-Ling Su) ； 林中天(Chung-Tien Lin)

《臺灣獸醫學雜誌》 31卷4期 (2005/12) Pp. 225-229

https://doi.org/10.7009/TVJ.200512.0225

摘要

一隻十歲齡、未結紮的黑色混種公犬由於左眼角膜水腫及眼球腫大，而被轉診至台大動物醫院就診。經給予降眼壓藥物局部點眼及青光眼減壓手術均無顯著療效後，建議畜主進行末期青光眼之全眼球摘除手術。術後將摘下之眼球送作病理切片，病理診斷為具惡性特徵之葡萄膜黑色素瘤。在全眼球摘除手術的四個月後，畜主發現病犬在背上的皮膚出現一皮下腫塊，同時牙齦上也發現有一黑色增生團塊，放射線檢查發現在腹腔中有非常巨大的團塊，並於肺門附近發現有密度增加的現象。在開腹探查手術中摘除源自腸繫膜之腹腔腫塊和切除牙齦團塊後，檢體送作病理學診斷，結果為轉移之惡性黑色素瘤。牙齦腫塊於第二次手術一個月後又再度復發，由於遠端多處轉移之惡性黑色素瘤的預後極差，所以畜主決定讓病犬接受安樂死。

關鍵字

狗 ； 青光眼 ； 轉移 ； 葡萄膜黑色素瘤

並列摘要

A ten year-old intact male mongrel dog with black hair coat was referred to The National Taiwan University Veterinary Hospital (NTUVH) because of enlarged left eye with corneal edema. Following anti-glaucoma medical treatment and pharmacologic ablation of ciliary body with failure, the eye with end-stage glaucoma was enucleated. An uveal melanoma with malignant features was diagnosed at surgery and pathological examination. Four months after surgery, subcutaneous masses on its back and gingiva were noted. Radiographic examination revealed a huge mass, with increased density in hilus of the lung. Laparotomy and masses excision from the abdomen was performed. The malignant melanoma with widespread metastasis was diagnosed following pathological results of the masses. The gingival mass recurred one month after surgery and the owner decided euthanasia of the dog.

並列關鍵字

Dog ； Glaucoma ； Metastasis ； Uveal melanoma