Germicidal Activity and Chicken Toxicity of Chlorine Dioxide

二氧化氯對微生物的殺滅力和對鷄毒性

林茂勇(Maw-Yeong Lin) ； 黃慧禎(Hui-Chen Huang) ； 蘇怡蓁(I-Chen Su) ； 胡妙菁(Maio-Chin Hu) ； 蔡岱枷(Dai-Jia Tsai) ； 黎玉葉(Yu-Ye Li) ； 陳瑞雄(Rey-Shyong Chen) ； 蔡向榮(Hsiang-Jung Tsai)

《臺灣獸醫學雜誌》 34卷3期 (2008/09) Pp. 142-148

https://doi.org/10.7009/TVJ.200809.0142

摘要

本試驗進行二氧化氯(CIO2)在乾淨水中和污濁水中分別對79株細菌和31株酵母菌和4株病毒的殺滅力及以飲水或噴灑方式投予鷄隻CIO2之安全性評估。發現CIO2在乾淨稀釋液中對細菌和酵母菌的中間致死濃度(MLC50)分別為9.4和8.4ppm，CIO2在污濁稀釋液中對細菌和酵母菌的MLC50分別為39.9和24.3ppm，CIO2之殺滅新城病病毒、H6N1型家禽流行性感冒病毒、傳染性支氣管炎病毒和傳染性華氏囊炎病毒的濃度分別為1.2、1.2、2.5和1.2ppm。全部來亨鷄每天以飲水或皮膚噴霧投予10mL含500、250、125、62.5或0ppm的CIO2連續7天並未顯現任何異常直至投予後14天。CIO2對細菌、酵母菌和病毒具高度殺滅力，但不會對鷄造成任何毒性。

關鍵字

二氧化氯 ； 微生物殺滅劑 ； 病毒殺滅劑 ； 細菌殺滅劑

並列摘要

The bactericidal, fungicidal and virucidal activity of chlorine dioxide (CIO2) against 79 bacteria, 31 yeasts and 4 viruses were evaluated under clean and dirty conditions. The safety of CIO2 to chickens given by drinking water or skin spraying was also evaluated. In clean diluent condition, the median lethal concentration (MLC50) of CIO2 against bacteria and yeast was 9.4 and 8.4 ppm, respectively. In dirty diluent condition, the MLC50 of CIO2 against bacteria and yeasts was 39.9 and 24.3 ppm, respectively. The virucidal activity of CIO2 against 100 median embryo lethal dose (100 ELD50) of Newcastle disease virus, avian influenza virus, infectious bronchitis virus and infectious bursal disease virus was 1.2, 1.2, 2.5 and 1.2 ppm, respectively. All the leghorn chickens continuously given with 10 mL of 500, 250, 125, 62.5 or 0 ppm of CIO2 in drinking water or on skin spraying for 7 days were not found showing any abnormality at 14 days post medication. Chlorine dioxide provides high bactericidal and virucidal activity without resulting any toxicity to the chickens.

並列關鍵字

chlorine dioxide ； germicide ； virucide ； bactericide