健檢民眾非酒精性脂肪肝盛行率之分析－以台中市一醫學中心為例

Analysis of Nonalcoholic Fatty Liver in Patients Receiving Health Checkups: A Hospital-Based Study

賴世偉(Shih-Wei Lai) ； 廖光福(Kuan-Fu Liao) ； 黃金財(Kim-Choy Ng)

《輔仁醫學期刊》 3卷2期 (2005/06) Pp. 75-80

摘要

Background and Purpose: In order to explore the prevalence of nonalcoholic fatty liver in Taichung, an urban area in Taiwan and further to establish a database for evidence-based medicine. Methods: This was a hospital-based, cross-sectional study. We retrospectively analyzed patients receiving health checkups at 1 medical center located at Taichung, west-central Taiwan from January 2000 to December 2002. Subjects who habitually drank alcohol were excluded. In total, 3028 people were enrolled in this study, and they were divided into 3 age groups: 20~39, 40~64, and (65 years old. Fatty liver was diagnosed by the gastroenterologists using sonography. The t-test and Chi-square test were used to assess the significance in differences for continuous and categorical variables, respectively. We also used logistic regression to assess the dose-response trend. Results: There were 1618men (53.4%) and 1410women (46.6%). The mean age was 49.6 (12.4 (range, 20~87) years. Overall, the prevalence of nonalcoholic fatty liver was 40.8% (48.2% in men and 32.3% in women, p＜0.0001). Among the 3 different age groups (20~39, 40~64, and (65 years), the prevalence of nonalcoholic fatty liver was 44.6%, 51.0%, and 38.3% in men (p=0.002) and 10.2%, 35.9%, and 46.4% in women (p＜0.0001), respectively. The logistic regression showed that the prevalence of nonalcoholic fatty liver increased with age in women (p＜0.0001, 95% confidence interval: 0.075~0.111), but not in men. Conclusion: The prevalence of nonalcoholic fatty liver was found to be relatively high in Taichung. We hope this study can provide basic information for further surveys of nonalcoholic fatty liver in Taiwan.

關鍵字

非酒精性脂肪肝 ； 實證醫學 ； 盛行率 ； 台灣

並列摘要

Background and Purpose: In order to explore the prevalence of nonalcoholic fatty liver in Taichung, an urban area in Taiwan and further to establish a database for evidence-based medicine. Methods: This was a hospital-based, cross-sectional study. We retrospectively analyzed patients receiving health checkups at 1 medical center located at Taichung, west-central Taiwan from January 2000 to December 2002. Subjects who habitually drank alcohol were excluded. In total, 3028 people were enrolled in this study, and they were divided into 3 age groups: 20~39, 40~64, and (65 years old. Fatty liver was diagnosed by the gastroenterologists using sonography. The t-test and Chi-square test were used to assess the significance in differences for continuous and categorical variables, respectively. We also used logistic regression to assess the dose-response trend. Results: There were 1618men (53.4%) and 1410women (46.6%). The mean age was 49.6 (12.4 (range, 20~87) years. Overall, the prevalence of nonalcoholic fatty liver was 40.8% (48.2% in men and 32.3% in women, p＜0.0001). Among the 3 different age groups (20~39, 40~64, and (65 years), the prevalence of nonalcoholic fatty liver was 44.6%, 51.0%, and 38.3% in men (p=0.002) and 10.2%, 35.9%, and 46.4% in women (p＜0.0001), respectively. The logistic regression showed that the prevalence of nonalcoholic fatty liver increased with age in women (p＜0.0001, 95% confidence interval: 0.075~0.111), but not in men. Conclusion: The prevalence of nonalcoholic fatty liver was found to be relatively high in Taichung. We hope this study can provide basic information for further surveys of nonalcoholic fatty liver in Taiwan.

並列關鍵字

nonalcoholic fatty liver ； evidence-based medicine ； prevalence ； Taiwan