As an actor of a tragedy, the cancer patients facing the challenge of the disease, even with tumor metastasis, lost their faith and felt hopeless. This patient was a single mother who suffered from lung cancer with bone metastasis. The whole challenge attacked her soul and body, and result in depression, hopelessness, crying and suicide. The nursing process was from May 9(superscript th) to May 22 2008. The author help the patient to control symptoms, encouraged to express depressive mood and feeling, empathy the hopelessness initiatively, guided the patient and her son explore the real meaning of live, help them to cherish their life. According to the experience, it could help us to increase the caring of ability spirit mind, the author helped to provide unique of holistic care.