Autonomy of psychiatric patients is often ignored and neglected. The purpose of this study was to understand the need for autonomy of psychiatric patients in the day hospital of a regional hospital. In this study, focus group interview was used to investigate the need for autonomy of ten psychiatric patients. There were four sixty-minute interviews during the study period. All the processes were tape-recorded. Qualitative content analysis was applied in this study. Four needs were concluded, including providing information, choosing activity therapy, involving policy of ward and relationship of psychiatric work. The results help health care workers to gain a deeper understanding of the need for autonomy of psychiatric patients and help patients to empower their autonomy.