Intraarticular Triamcinolone Hexacetonide Injection in Children with Chronic Arthritis: A Survey of Clinical Practice

關節內類固醇注射於兒童慢性關節炎的應用

楊美慧(Mei-Hui Yang) ； 李文益(Wen-Li Lee) ； 陳力振(Li-Chen Chen) ； 林思偕(Syh-Jae Lin) ； 黃璟隆(Jing-Long Huang)

《Acta Paediatrica Sinica》 40卷3期 (1999/06) Pp. 182-185

https://doi.org/10.7097/APS.199906.0182

摘要

針對幼年期慢性關節炎，關節內注射類固醇已被證實爲有效且副作用極少的一種輔助治療。本院收集了11位幼年期慢性關節炎的小朋友，均在非類固醇藥物治療至少3個月無效後，接受關節內類固醇注射療法，注射後至少追蹤6個月。大部分關節炎在2天到2星期內達到緩解，尤其是少關節性關節炎，此外沒有任何副作發生。因此，關節內類固醇注射療法是一種快速又安全的輔助療法。

關鍵字

幼年期慢性關節炎 ； 關節內類固醇注射療法

並列摘要

To assess the efficacy of the intraarticular steroid(IAS) injection in the management of arthritis and the possible related complications in children with chronic arthritis. We evaluated 11 children of chronic arthritis (4 girls and 7 boys), age of onset ranged from 2~13.6 years, who had persistent arthritis treated with lAS from November 1994 to June 1997. The results of injections showed that the beneficial effect was noted within one day to 2 weeks without significant adverse reactions, remission exceeding 6 months was seen in 10 of 11 patients (in 14 of 18 joints). According to subgroups of chronic arthritis, the remission rate of lAS injection in children with pauciarticular arthritis reached 100%. A significant fall in C-reactive protein (CRP) between pre-and post-lAS injection (p=O.O3), but there were no differences in hemoglobin (Hb), white blood cells (WBCs), thrombocytes (Pits), erythrocyte sedimentation rate (ESR) and osteocaicin level. No injection-related complications were found. In conclusion, the lAS injection was an effective and safe treatment in children with chronic arthritis with no obvious complications especially in pauciarticular arthritis.

並列關鍵字

chronic arthritis ； intraarticular steroid injection