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【論文摘要】Association Between Temporomandibular Disorder and Chronic Low Back Pain: A Nationwide, Population-Based Cohort Study in Taiwan

【論文摘要】顳顎關節障礙與慢性下背痛相關性探討:以臺灣健保資料為例

摘要


Background and Purpose: Chronic low back pain (CLBP) is high prevalent disease with some comorbidities and is potential related with temporomandibular disorder (TMD). This nationwide matched cohort population-based study aims to investigate the association between CLBP and TMD. Methods: A total of 33,820 patients with newly diagnosed CLBP between January 1, 2000 and December 31, 2000 were enrolled from the National Health Insurance Research Database (NHIRD) of Taiwan, along with 101,460 (1:3) controls matched for sex and age. The multivariate Cox proportional hazards regression analysis was used to determine the risk of TMD between CLBP and control group. Kaplan-Meier method with the log-rank test was used for the cumulative risk of TMD between two groups for 15 years follow up. Results: In the results of this study, the event rate of TMD for the CLBP cohort (14.36 per 100,000 person-years) was higher than that for non-CLBP controls (7.06 per 100,000 person-years). The Cox regression model revealed that the CLBP cohort was more likely to develop TMD: the adjusted hazard ratio (HR) is 1.436 (95% confidence interval [CI] = 1.025–2.013, p = 0.003), after adjusting for sex, age, monthly income, education, marital status, seasons, urbanization level, geographic region of residence, medications, levels of hospitals, and comorbidities. Conclusion: Patients with CLBP were at higher risk to develop TMD and almost 1.5-fold than non-CLBP group. Clinical Relevance: Our findings might remind the clinicians who care the patients with CLBP should be aware of the occurrence of TMD as comorbidity.

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