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Does platelet-rich plasma gel augmentation improve clinical outcomes in patients aged 50 years or older receiving hip arthroscopy for symptomatic femoroacetabular impingement?

本文另有預刊版本,請見:10.6492/FJMD.202006/PP.0003

摘要


Background: Good outcomes can be obtained by hip arthroscopy for the treatment of symptomatic femoroacetabular impingement (FAI). However, old age was considered as a predictor of poor outcomes. Purpose: The purpose of the study was to evaluate if platelet-rich plasma (PRP) gel can improve clinical outcomes in patients aged 50 years or older who received hip arthroscopy for FAI. Methods: We retrospectively evaluated patients aged 50 years or older at the time of hip arthroscopy for symptomatic FAI between January 2013 and June 2016 in our institute. The exclusion criteria included a dysplastic hip, preoperative joint space less than 2 mm, with a previous operative history on the same hip, and less than 12-month follow-up after the index surgery. Demographic data, preoperative joint space, intra-operative findings, preoperative and postoperative modified Harris Hip Score (mHHS) and visual analogue scale (VAS) were compared between patients with PRP gel augmentation during hip arthroscopy and patients without PRP gel augmentation. In addition, the multivariate linear logistic regression analysis was used to determine if PRP gel, joint space and acetabular microfracture had an impact on clinical outcomes. Results: Eleven patients with PRP gel augmentation and 16 patients without PRP gel augmentation were included in this study. A significant improvement of mHHS was observed in both groups, but the non-PRP group had significantly greater improvement of mHHS than the PRP group. In the multivariable logistic regression analysis, the use of PRP gel, the acetabular microfracture and the preoperative joint space were not significantly associated with the improvement of mHHS and VAS. Conclusion: The beneficial effect of PRP gel augmentation could not be observed in patients aged 50 years or older following hip arthroscopy for symptomatic FAI in the current study.

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