上轉換發光材料應用於生醫檢測及生物造影

Upconversion Luminescence Materials Used in Biomedical Testing and Bio-imaging

詹明賢(Ming-Hsien Chan) ； 李伊容(I-Jung Lee) ； 劉如熹(Ru-Shi Liu)

《化學》 75卷1期 (2017/03) Pp. 25-35

https://doi.org/10.6623/chem.2017002

摘要

據近年衛福部統計，惡性腫瘤已多年蟬聯國人死亡率之首，其次為心臟疾病與腦血管疾病，上述疾病皆好發於年長者。現今疾病檢測，仍以潛血檢查、組織切片與放射線造影為主，檢測方法仍有改善空間，尤其對於年長者之檢測更應考慮過程中所帶來之不便。故近年來，學界正積極研究新型輔佐性檢測法，其中尤以發光材料之檢測造影備受矚目，因其相較於傳統療法具低侵襲性與低副作用之優點。本文將針對上轉換發光材料應用於生醫檢測及生物造影之未來發展作一簡單介紹。

關鍵字

上轉換發光 ； 生醫檢測 ； 生物造影

並列摘要

According to the recent statistics of the Ministry of Health and Welfare, malignant tumors have topped the list of causes of death, followed by heart diseases and cerebrovascular diseases, which occurs in elderly men and women. Current methods for disease detection such as blood examination, tissue biopsy and radiography still need to be improved. The diagnostic process is somewhat inconvenient and should be considered, particularly in elderly. In recent years, researchers have been working on the study of new adjuvant detection method, especially on the detection of luminescence material imaging attention. Compared to traditional methods, the new approach is less invasive and has low side effects. This review article aims to give a brief introduction to the future development of upconversion luminescent materials in biomedical testing and bioimaging.

並列關鍵字

Upconversion luminescence ； Biomedical testing ； Bioimaging