- 期刊
- OpenAccess
Isomalto-Oligosaccharides Improve Constipation in Peritoneal Dialysis Patients-A Randomized, Double-Blind, Placebo-Controlled Trial
摘要
BACKGROUND: Chronic constipation is a common complication in peritoneal dialysis (PD) patients. This study aims to evaluate the effects of oral isomalto-oligosaccharides (IMO) on chronic constipation in PD patients. METHODS: Fifty-six PD patients treated with laxatives were randomized to receive oral 90% isomalto-oligosaccharides (IMO 90) or placebo for 8 weeks. Anthropometric and biochemical data, dietary intake details, defecation frequency, the Patient Assessment of Constipation Symptom Questionnaire (PAC-SYM), and the Patient Assessment of Constipation Quality of Life Questionnaire (PAC-QOL) questionnaires were assessed before and after the study in both groups. RESULTS: The IMO 90 group needed significantly lower dose of laxatives after use of IMO 90. The PAC-SYM and PAC-QOL questionnaires revealed significant improvements in constipation-related symptoms and quality of life in the study group. CONCLUSION: Oral IMO administration is a useful adjunct to improve constipation in PD patients.
延伸閱讀
- Chang, W. N. (2007). Cost-Effectiveness Analysis and Optimal Budget Allocation of Peritoneal Dialysis and Haemodialysis Using in End Stage Renal Disease Treatment [master's thesis, National Tsing Hua University]. Airiti Library. https://doi.org/10.6843/NTHU.2007.00216
- Tjiong, H. L., Zijlstra, F. J., Rietveld, T., L.Wattimena, J., Huijmans, J. G. M., Swart, G. R., & Fieren, M. W. J. A. (2007). Peritoneal Protein Losses and Cytokine Generation in Automated Peritoneal Dialysis with Combined Amino Acids and Glucose Solutions. Mediators of Inflammation, 2007(), 436-440. https://doi.org/10.1155/2007/97272
- 黃思惟（2022）。The associations of plasma trace elements with inflammatory response, antioxidant capacities and oxidative stress in hemodialysis and peritoneal dialysis patients〔碩士論文，中山醫學大學〕。華藝線上圖書館。https://doi.org/10.6834/csmu202200220
- Huang, C. F. (2021). Effects of stepwise initiation of peritoneal dialysis compared with conventional peritoneal dialysis, A Systematic review and Meta-analysis [master's thesis, National Taiwan University]. Airiti Library. https://doi.org/10.6342/NTU202104493
- 吳珮瑜（2020）。Shorter time between symptoms onset and patient notify peritoneal dialysis center improve outcome of peritoneal dialysis peritonitis〔碩士論文，高雄醫學大學〕。華藝線上圖書館。https://www.airitilibrary.com/Article/Detail?DocID=U0011-1807202015554100