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經由細針抽吸細胞學診斷Kikuchi氏病-病例報告

Diagnosis of Kikuchi's Disease by Fine Needle Aspiration Cytology – Case Report

摘要


Kikuchi氏病,又稱為組織球壞死性淋巴結炎,是一種病因未明的良性淋巴結病變。臨床表現以多發性頸部淋巴結腫大為主,但易與惡性淋巴瘤及其他疾病混淆。在以往必須以淋巴結切片來確定診斷,但切片檢查較具侵犯性。而細針抽取吸細胞學對頭頸部腫瘤的評估,具有高敏感性、專一性、準確性、快速、安全及非侵犯性等優點。本文特別報告1例經細針抽吸細胞學檢查,即可診斷Kikuchi氏病的案例,並回顧文獻,歸納以細針抽吸術來診斷Kikuchi氏病的細胞學特徵。並提出其與惡性淋巴瘤及其它疾病在細胞學上的差異,以作為鑑別診斷的參考。且籍此提出患者若有典型的臨床表徵及典型的細針抽吸細胞學特徵,單由淋巴結的細針抽吸細胞學即可診斷Kikuchi氏病,應可避免侵犯性的淋巴結切片。

並列摘要


Kikuchi’s disease, also known as histiocytic necrotizing lymphadenitis, is a benign, self-limiting disorder and usually presented with cervical lymphadenopathy. The etiology is unknown. It is frequently mistaken as malignant lymphoma or some other disorders. The diagnosis is usually confirmed by lymph node biopsy. Diagnosis made by fine needle aspiration (FNA) cytology has rarely been reported in the literature. Herein, we reported a case of Kikuchi’s disease which was diagnosed by FNA cytology. We tried to organize the characteristic features of FNA cytology of this disease. We believed that in the patients present with characteristic sympotoms and cytologic features, Kikuchi’s disease might be diagnosed by FNA cytology alone. Therefore, the lymph node biopsy could be avoided.

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