Ten-Year Registry of Native Kidney Biopsy from a Single Center in Taichung

Kuang-Chin Hsiao ； Jong-Da Lian ； Shen-Wen Wu ； Tung-Wei Hung ； Chih-Kuang Lin ； Mei-Chin Wen ； Horng-Rong Chang

《Acta Nephrologica》 26卷2期 (2012/06) Pp. 68-73

https://doi.org/10.6221/AN.2011022

並列摘要

BACKGROUND: Renal biopsy plays an important role in diagnosis of renal disease, especially in nephrotic syndrome. IgA nephropathy had been the most common glomerular disease in the whole world. However, there were not many reports about the epidemiological incidence and causes of renal disease in Taiwan.METHODS: We performed a single-center, retrospective analysis of patients with renal disease that was documented by precutaneous renal biopsy from October 2000 to December 2010. Demographic data (age, gender), laboratory investigations such as serum urea, serum creatinine, proteinuria, haematuria, 24-hour urinary protein, and creatinine clearance, and clinical diagnosis were collected for analysis.RESULTS: There were 444 native kidney biopsies performed, 238 males (53.6%) and 206 females (46.7%). The average age of patients was 47.6 years. The most common clinical presentation as an indication for renal biopsy was nephrotic syndrome (52%). Membranous nephropathy (17.5%) was the most common glomerular disease and the most frequent cause (29.8%) of nephrotic syndrome. Primary glomerular disease accounted for 55% of all biopsies and membranous nephropathy was the most frequent cause (31.7%) of the primary glomerular disease. Lupus nephritis was the most frequent secondary glomeurlonephritis (53.21%).CONCLUSIONS: Instead of IgA nephropathy, membranous nephropathy was the most common primary glomerular disease and lupus nephritis was the most common secondary glomerulonephritis in our analysis. The high prevalence of membranous nephropathy could be due to older age and higher incidence of patients with nephrotic syndrome in our database.

並列關鍵字

native renal biopsy ； nephrotic syndrome ； membranous nephropathy

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