Long-Term Follow-Up of Cervical Cancer Patients Treated with Preloaded Radium Brachytherapy from 1977 to 1983

在後荷治療技術發展之前，子宮頸癌的放射線治療一直以前荷式鐳錠治療為主，即使在數十年後的今天，這些經驗仍是將來發展進步的參考。本文討論自1977到1983年間我們以前荷式鐳錠治療做子宮頸癌腔內近接放射線治療的結果，以便與以後的後荷式治療有所比較。這篇回溯性的分析共有347個病例，其五年和十年的保險存活率分別為：第一期：89.2%和456%，第二期：67.8%和53.5%，第三期：48.9%和40.3%。共有8個病例有尿道和直腸方面的後遺症，它們發生在治療後一年至數年不等。有5個病例在照射後1到11年發生了第二個腫瘤，分別為：2個乳癌，1個多發性骨髓瘤，1個肺部鱗狀細胞癌，1個腹壁上的軟組織肉瘤。在後荷治療技術發展之前，子宮頸癌的放射線治療一直以前荷式鐳錠治療為主，即使在數十年後的今天，這些經驗仍是將來發展進步的參考。本文討論自1977到1983年間我們以前荷式鐳錠治療做子宮頸癌腔內近接放射線治療的結果，以便與以後的後荷式治療有所比較。這篇回溯性的分析共有347個病例，其五年和十年的保險存活率分別為：第一期：89.2%和456%，第二期：67.8%和53.5%，第三期：48.9%和40.3%。共有8個病例有尿道和直腸方面的後遺症，它們發生在治療後一年至數年不等。有5個病例在照射後1到11年發生了第二個腫瘤，分別為：2個乳癌，1個多發性骨髓瘤，1個肺部鱗狀細胞癌，1個腹壁上的軟組織肉瘤。

關鍵字

子宮頸癌；前荷式鐳錠；腔內放射治療

並列摘要

Before the afterloading technique was available, preloaded radium was the mainstay for radiotherapy of carcinoma of the uterine cervix. After many decades of clinical practice, the experience is still useful as references in t he developments of brachytherapy for cervical cancer. This study reports our results during 1977 through 1983 when preloaded radium was used for intracavitary brachytherapy. Comparison is made with results treated with afterloading technique in later years. Three hundred and forty seven cases were in eluded in this retrospective analysis. The 5-year and 10-year actuarial survival rates were: stage I 89.2% and 45.6%; stage II 67.8% and 53.5%; and stage III 48.9% and 40.3%, respectively. There were 8 cases of major complications of the urinary tract and rectum which occurred one or more years after treatment. Five patients were diagnosed to have second malignant tumor 1-11 years after irradiation. These tumors include 2 breast cancers, 1 multiple myeloma, I squamous cell carcinoma of the lung, and 1 soft tissue sarcoma of the abdominal wall.

並列關鍵字

Cervical cancer ； Preloaded radium ； Intracavitary radiation therapy

國際替代計量

Long-Term Follow-Up of Cervical Cancer Patients Treated with Preloaded Radium Brachytherapy from 1977 to 1983

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