- 期刊
- OpenAccess
Frequency Variation of Ventricular Fibrillation May Help Predict Successful Defibrillation in a Rat Model of Cardiac Arrest
摘要
Background: To evaluate whether the frequency variation of ventricular fibrillation (VF) helps to predict successful defibrillation in a rat model of cardiac arrest. Methods: VF was induced in rats followed by cardiopulmonary resuscitation and then defibrillation. The electrocardiographic signals of 30 rats with first-shock success were obtained from our previous animal experiments, and 300 rats without first-shock success were selected as control. The VF waveform immediately before the first defibrillation was analyzed. Results: Eighty-eight percentages of the frequency variations of an electrocardiogram (ECG) record falling in the range -9.5-9.5 Hz was selected with sensitivity of 0.8, specificity of 0.583, and area under curve (AUC) of 0.708. Compared with amplitude spectrum area (AMSA) (sensitivity = 0.767, specificity = 0.547, and AUC = 0.678), combining frequency variation and AMSA significantly increases the predictability with sensitivity of 0.933, specificity of 0.493, and AUC of 0.732 (p = 0.005). Conclusions: The frequency variation of VF may serve a useful parameter to predict defibrillation success.
延伸閱讀
- Chang, C. J., Liou, T. H., Tsai, W. T., Hsu, C. F., Chong, W. S., Sun, J. T., Yen, T. H., Chiang, W. C., & Chang, C. C. (2020). Clinical and Hematological Predictors for Return of Spontaneous Circulation in Patients With Out-of-Hospital Cardiac Arrest. Journal of Acute Medicine, 10(2), 51-59. https://doi.org/10.6705/j.jacme.202006_10(2).0001
- 張適恆（2010）。Heart Rate Variability during Therapeutic Hypothermia and Post-resuscitation Outcomes in Animals Subjected to Experimental Cardiac Arrest〔碩士論文，國立臺灣大學〕。華藝線上圖書館。https://doi.org/10.6342/NTU.2010.10289
- Alla, V. M., Anand, K., Hundal, M., Chen, A., Karnam, S., Hee, T., Hunter, C., Mooss, A. N., Esterbrooks, D., & Mohiuddin, S. M. (2010). Impact of Moderate to Severe Renal Impairment on Mortality and Appropriate Shocks in Patients with Implantable CardioverterDefibrillators. Cardiology Research and Practice, 2010(), 32-37. https://doi.org/10.4061/2010/150285
- 林沛昀、呂學禎、張家禎、林宜美（2018）。The Effects of Heart Rate Variability Biofeedback on Patients with Coronary Artery Disease and Premature Ventricular Contractions。台灣家庭醫學雜誌，28(3)，129-141。https://doi.org/10.3966/168232812018092803003
- Patoulias, D. (2021). SGLT-2 Inhibitors Beneficial Effects on Ventricular Repolarization May Be Protective against Atrial Fibrillation Occurrence. Acta Cardiologica Sinica, 37(3), 323-323. https://doi.org/10.6515/ACS.202105_37(3).20210313A