This paper describes the experience of nursing a patient with lymphoma who was undergoing chemotherapy. Four examinations that are used in traditional Chinese medicine are performed. Data were collected by observation, interview, physical assessment, and medical records. During the period of nursing from July 8, 2011 to August 18, 2011, three main health problems were identified. They were (1) pain, (2) insomnia and (3) potential risk of infection. The focus of the nursing was on providing health education to reduce pain and insomnia and to prevent infection, and thereby to help the patient face the treatment process. The experience of nursing and caring for a patient who was undergoing chemotherapy provides a reference for clinical nurses.