Medicinal Plants as Treatment Option of Male Reproductive Dysfunctions

Faustin Pascal Tsagué Manfo ； Edouard Akono Nantia ； Sara Nathalie Edjenguèlè Béboy ； Paul Fewou Moundipa ； Michel Pugeat4 ； Paulus S. Wang

《Adaptive Medicine》 7卷2期 (2015/06) Pp. 57-72

https://doi.org/10.4247/AM.2015.ABF107

並列摘要

Infertility accounts for 8-12% among couples wordwide. Male factor contributes for about 50% of infertility cases, and medicinal plants-integral part of adaptive medicine-, which represents the most ancient form of therapy, have been widely used by affected males. This paper reviews current information on the use of medicinal plants in the improvement of male reproductive function. Collectively the reviewed information provide suggestive evidence for the effectiveness of three medicinal plants in control of dysfunctions related to male reproductive function in humans, including erectile dysfunction, hormone imbalances, and impairment of spermatogenesis. Other medicinal plants and formulations herein reviewed showed promising preliminary results, and may lead to development of supplementary efficacious and safe herbal formulations for treatment of male reproductive disorders. Generally, the medicinal plants and related formulations exhibit adaptogenic or antioxidant properties, which may also assist in prevention and treatment of oxidative stress-induced infertility. There is however the need to rationalize the use of the medicinal plants with potential therapeutic effect, with respect to confirmation of their efficacy in clinical studies, in addition to dose-response effects and their mechanistic actions.

並列關鍵字

adaptogen ； medicinal plant ； male infertility ； reproductive dysfunctions ； spermatogenesis