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台灣超高磁場液態核磁共振核心簡介及其在基因體醫學之應用

Taiwan Ultra High-Field Solution NMR Core Facility and Applications in Genomic Medicine

摘要


核磁共振光譜學是應用最廣泛、最重要的物理技術,其應用範圍涵蓋物質定性、化學分子的結構鑑定、生理的新陳代謝、生化巨分子的結構動性與功能以及磁振造影等,它已成為生、醫、理、工各領域研究及應用不可或缺的先進技術。本文針對台灣設置於中央研究院生物醫學科學研究所最先進的高磁場液態核磁共振核心(HFNMRC)之最近發展作一簡單介紹,該中心開放全國有需求的學術及產業界使用,提供各項技術服務及諮詢。

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並列摘要


NMR spectroscopy is perhaps the most versatile and most important physical technique. Its applications encompass material characterization, chemical structure determination, metabolism, biomacromolecular structure dynamics and function, and MRI etc. It has become an indispensible advanced tool in biomedicine, natural science, and engineering. Here we briefly introduce the recent developments in ultra high-field solution NMR at the High Field NMR Center (HFNMRC) at Academia Sinica. HFNMRC is open to all qualified users from academic and industry alike in Taiwan.

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