Depression during the period of pregnancy has been wide concern. During American research results, 1/10 of will suffer from depression parturient, and 86% of the lack of correct drug therapy. Pregnancy from depression may result in personal and family problems, even for embryos would constitute an injury. Many study from the depression had report that it will effect the baby's hormones (like, stress hormones), cause decrease the birth weight, prematurely and impaired of fetal brain. Iodine-123-ADAM (((2-2-(amino-4-iodophenyl) thio) benzyl] Dimethylamine), functional diagnostic molecular imaging agent, could provide non-invasive and real-time imaging technologies. Quantity of SERT with ADAM could apply for early diagnosis and earlier correct medical treatment. But, during pregnancy with nuclear medical radiopharmaceuticals will worry about the passed the placental to the fetus, or stuck in the mother organs to format the in vitro exposure to the fetus. In this study used rats as the animal model to assess the radioactive in pregnancy. In reproductive and developmental toxicity, including assess of fecundity, embryo toxicity, and the possibility of teratoma, etc. We wish to give an assessment of clinical safety of parturient in using Iodine-123-ADAM.