Purpose: this study was to examine whether supplementation of Co Q10 could lower formation of lipid peroxides, muscular damage, and aerobic exercise performance in athletes. Methods: Sixteen female soccer players were assigned to either the Co Q10 (120 mg per day) group or to the placebo group by matching their maximal oxygen uptakes (VO(subscript 2max)). Sixty minutes of endurance exercise at 65% VO(subscript 2max) followed by exercise at 90% VO(subscript 2max) until exhaustion was performed on a treadmill before and after a 4-week treatment period. The administration of either Co Q10 or placebo and the conduction of exercise tests were done double blinded. Results: there were no difference of malondialdehyde (MDA) after exercise between Co Q10 and placebo groups (p>.05). There were also no significant difference of increased percentage in creatine kinase (CK) after exercise between Co Q10 and placebo groups (p<.05). Conclusions: the results could not prove directly that Co Q10 supplementation might suppress the increase of lipid peroxides during exercise, and showed a trend of reduce creatine kinase, an index of muscular damage. The results indicated that four weeks Co Q10 supplementation did not affect aerobic exercise indices such as maximal heart rate, maximal oxygen consumption, respiratory exchange ratio, and time to exhaustion.
Purpose: this study was to examine whether supplementation of Co Q10 could lower formation of lipid peroxides, muscular damage, and aerobic exercise performance in athletes. Methods: Sixteen female soccer players were assigned to either the Co Q10 (120 mg per day) group or to the placebo group by matching their maximal oxygen uptakes (VO(subscript 2max)). Sixty minutes of endurance exercise at 65% VO(subscript 2max) followed by exercise at 90% VO(subscript 2max) until exhaustion was performed on a treadmill before and after a 4-week treatment period. The administration of either Co Q10 or placebo and the conduction of exercise tests were done double blinded. Results: there were no difference of malondialdehyde (MDA) after exercise between Co Q10 and placebo groups (p>.05). There were also no significant difference of increased percentage in creatine kinase (CK) after exercise between Co Q10 and placebo groups (p<.05). Conclusions: the results could not prove directly that Co Q10 supplementation might suppress the increase of lipid peroxides during exercise, and showed a trend of reduce creatine kinase, an index of muscular damage. The results indicated that four weeks Co Q10 supplementation did not affect aerobic exercise indices such as maximal heart rate, maximal oxygen consumption, respiratory exchange ratio, and time to exhaustion.