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Primary Radiotherapy Treatment Results of Maxillary Sinus Squamous Cell Carcinoma

上頷竇扁平細胞癌之放射治療結果

Abstracts


目的:評估上頷竇癌用不同治療方後的結果。
材料與方法:從1977至1991年61個上頷竇扁平細胞中,有11個病人(18%)是T3,50個病人(82%)是T4。其中18個病人只作放射治療,32個病人術後追加放射治療,11個病人合併放射治療,竇造口術及動脤內注射化學治療。
結果:以上三組病人五年存活率分別為5.6%,34.4%及54.5,具有明顯統計差別。在診斷時有淋巴轉移的病人,其五年存活率較無淋巴轉移病人明顯偏低(7.1%比36.2%)。多變數分析得出性別,治療方式,淋巴分期為顯著的預後因子。
結論:合併治療比只作放射治療有較好的五年存活率。

Parallel abstracts


Purpose: Evaluating 5-year survival rates of maxillary sinus squamous cell carcinoma treated by different methods.
Materials and Methods: From 1997 to 1991, 61 patients of maxillary sinus squamous cell carcinoma were included in our study. There were 11 patients with T3 (18%) disease and 50 patients with T4 (82%) disease. Eighteen patients (29.5%) were treated by radiotherapy alone (RT), 32 patients (52.5%) by combined surgery and radiotherapy (SRT) and 11 patients (18.0%) by combined radiotherapy with intra-arterial 5-FU infusion chemotherapy and antrostomy drainage (CRT).
Results: Five-year survival rates were 5.6%, 34.4% and 54.5% in RT, SRT and CRT groups, respectively. Statistical significant difference (p<0.05) of survival rates was noted. Regional neck nodal metastasis at initial diagnosis carried significant worse survival results than initial NO state (7.1% vs. 36.2%, p=0.0003). Multivariate analysis revealed that treatment methods, sex and N stages significantly influenced the 5-year survival rate.
Conclusion: Combined treatment was superior to radiotherapy alone in 5-year survival rates.

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