- 期刊
放射線治療續發之上頜骨骨原性肉瘤－病例報告
Postirradiation Osteogenic Sarcoma of the Maxilla - Case Report
摘要
骨原性肉瘤是一種少見的惡性腫瘤，以發生於小孩及青少年為主，最常見於長骨的骨幹骺端，尤其是下肢，侵犯頭頸部者並不常見，因放射線治療而引發的頭頸部骨原性肉瘤更是罕見。根據文獻統計，此種放射線治療後續發性肉瘤的生率約在0.03%至0.22%之間。此種肉瘤對放射治療及化學治療的反應不佳，治療以手術根除為主。本院於民國84年12月經歷一鼻咽癌經放射治療後引起左側上頷骨骨原性肉瘤的病例，患者經左側上頜骨全切除後，現於門診追蹤治療，無復發跡象。
並列摘要
Osteogenic sarcoma is an uncommon malignant neoplasm which is usually seen in teenagers. The site of predilection is at the metaphysic of long bones, particularly of the lower limbs. Osteogenic sarcomas of the head and neck, especially the maxilla, are rare. The incidence of irradiation-induced sarcoma is between 0.03% and 0.22%. The treatment of choice for postirradiation sarcoma is radical operation. It is resistant to radiotherapy or chemotherapy. We report a 44-year-old male nasopha-ryngeal carcinoma patient who had received radiotherapy in 1990. He has suffered from nasal bleeding and palatal ulceration since 1995. Osteogenic sarcoma of the maxilla was confirmed by histology-cal examination. He received left total maxillectomy later. The post-operation course was smooth. There has been no evidence of recurrence till now.
延伸閱讀
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- Sivakumar, T. T., Jeevadhas, P., Raghavanpillai, V. B., Sivaraj, S., Joseph, A. P., & Denny, S. E. (2016). Recurrent osteosarcoma of maxilla presenting as fungating mass: A case report. International Journal of Case Reports and Images (IJCRI), 7(3), ii+149-153. https://doi.org/10.5348/ijcri-201623-CR-10610