Successful Treatment of Bilateral Chylothorax by Thoracoscopic Pleurodesis in a Child with Gorham's Disease

以胸腔鏡肋膜沾黏術成功治療－合併兩側乳糜胸之Gorham氏症病童

郭敏勇(Min-Yung Kuo) ； 周佳滿(Chia-Man Chou) ； 陳厚全(Hou-Chuan Chen)

《Mid-Taiwan Journal of Medicine》 13卷1期 (2008/03) Pp. 43-47

https://doi.org/10.6558/MTJM.2008.13(1).6

摘要

Gorham氏症是一以自發性骨質溶解症表現之罕見疾病。其中，乳糜胸更是其少見但常會致命的併發症。我們報告-4歲之Gorham氏症病例，藉由簡單且微創性之胸腔鏡肋膜沾黏術成功治療其兩側乳糜胸。同時，自發性骨質溶解之惡化亦藉由皮下注射干擾素而獲得控制。

關鍵字

Gorham氏症 ； 乳糜胸 ； 胸腔鏡肋膜沾黏術 ； 干擾素

並列摘要

Gorham's disease is an extremely rare bone disorder that manifests as spontaneous osteolysis with abnormal blood or lymphatic vessel growth. Chylothorax is not uncommon, but it can be fatal in patients with Gorham's disease. Herein, we report a 4-year-old boy with Gorham's disease who presented with bilateral chylothorax and spontaneous osteolysis extending from the lower thoracic spine to the sacrum with involvement of the right iliac bone. The condition was successfully treated by thoracoscopic surgery combined with mechanical and chemical pleurodesis. There was no evidence of recurrence of chylous pleural effusion at 3-year follow-up. His progressive osteolysis has been controlled by subcutaneous injection of interferon alpha-2b for the past 2 years.

並列關鍵字

Gorham's disease ； chylothorax ； thoracoscopic pleurodesis ； interferon