中年人的危機－代謝症候群

Crisis of the Middle-Aged Person-Metabolic Syndrome

劉秉一(Bing-Yi Liu)

《重症醫學雜誌》 9卷1期 (2008/03) Pp. 26-33

https://doi.org/10.30035/TCCM.200803.0004

摘要

代謝症候群是一群代謝異常的組合，包括有高血壓、高血糖、血脂異常與肥胖；代謝症候群又可稱為胰島素抗性症候群(insulin resistance syndrome)，原爲人體對抗肥胖的一種防禦機轉，其致病機轉主要還是導因於胰島素抗性的發生，符合代謝症候群的項目愈多，其所可能發生心血管疾病及糖尿病的風險愈高，其所合併的死亡率也愈高；代謝症候群的發生與年齡、生活型態（飲食、運動）與遺傳基因有關，而肥胖及缺乏運動的生活型態是重要的潛在危險因子。

關鍵字

代謝症候群 ； 胰島素抗性 ； 腹部肥胖

並列摘要

Metabolic syndrome is characterized by a cluster of metabolic disorders that occur together in one person. They include elevated blood pressure, glucose intolerance, atherogenic dyslipidemia and abdominal obesity. Metabolic syndrome is also called insulin resistance syndrome. The dominant underlying pathophysiology for this syndrome is insulin resistance. The emergence of metabolic syndrome is related to (1) aging (2) lifestyle (diet & physical activity) (3) genetic factors. Obesity and physical inactivity are important potential risk factors. People with metabolic syndrome are at increased risk for development of cardiovascular disease (CHD, stroke or PVD) and type 2 diabetes.

並列關鍵字

Metabolic syndrome ； Insulin resistance ； Abdominal obesity