123 neonates with surgical conditions were treated at National Taiwan University Hospital during the period of 1956 to 1965. Overwhelming majority of the cases were due to congenital malformation, among which anomalies of gastrointestinal tract and abdominal parietes predominated, About two third of the patients manifested symptoms during the first-three days of life, As vomiting, abdominal distention, impeded passage of meconium or constipation and respiratory distress were the four cardinal symptoms most commonly associated with these surgical conditions, whenever two or more of these symptoms are present in a neonate every effort should be made to rule out the surgical conditions, The results of treatment with an overall operative survival rate of 37.8% in this series were still far from satisfactory, though the survival rate for 1964-1965 was a little better, being 55.0%. Prematurity, multiple anomalies, and delayed surgery had partly contributed to the low survival rate. But the majority of the deaths were apparently due to complications, such as uncontrollable infection or sepsis, airway obstruction, poorly adjusted temperature and/or fluid supply as well as to the technical difficulties met with the tiny structure and phsiological immaturity of the neonate. Recommendations are made for the care of neonatal surgical patients basing on this critical study.