Congenital anomalies in surgical oncology practice

Shanmugam Subbiah ； Rajaraman ； Noushad Navin

《Edorium Journal of Surgery》 2期 (2015/12) Pp. 29-36

https://doi.org/10.5348/S05-2015-10-OA-8

並列摘要

Aims: Congenital anomalies are defects present at birth. The etiology is frequently multi factorial with interaction between genetic and environmental factors. Most anomalies are innocuous but some assume clinical significance that includes cancer risks, diagnostic dilemmas or surgical challenges. In this article, we present our experience with congenital anomalies, and review their embryological basis with emphasis on clinical significance and overcoming surgical challenges posed. Methods: Case records of 12,538 patients attending surgical oncology department were screened for congenital anomalies. Those with obvious congenital malformations and others with anatomical variations documented at surgery were included in the study. Results: Overall 21 anomalies were noted with a prevalence rate of less than 1%. The genitourinary system was the most affected 42% (n = 8) and multiple neurofibromatosis the most common disorder (n = 4). Pelvic kidney was the most common anomaly. In 57% (n = 12) patients, the defect was recognized at surgery, a preoperative suspicion based on imaging was possible only in two cases (pelvic kidney and situs inversus). Conclusion: Congenital Anomalies are rare, but present diverse problems to the oncologist. A majority are anatomical variations noticed at surgery an awareness and early recognition prevents surgical morbidity.

並列關鍵字

Clinical outcomes ； Congenital anomaly ； Surgical oncology