- 期刊
Gianotti氏病：與B 型肝炎病毒有關之小兒疾病
A Case Report of Gianotti's Disease
摘要
Gianotti氏病（又稱小兒丘疹性末端皮膚炎）在臺灣為一罕見之小兒疾病，此病一般發生於6個月~12歲之間的孩童，臨床上呈現特徵之皮疹，淋巴腺腫大及非黃疸性之急性肝炎伴HBsAg陽性。本文報告1典型病例，患兒為1歲2個月之男童，於顏面、四肢及臀部出現對稱性、非搔癢之紅色丘疹伴淋巴腺腫大。實驗室檢查發現HBsAg陽性，GOT 101IU/L，GPT 134IU/L，膽紅素在正常範圍內，血液中單核球達12%。3個月後HBsAg轉為陰性，且anti-HBc陽性，anti-HBs陰性，肝功能恢復正常。Gianotti氏病之皮膚病變及臨床特徵將在本文中評加述說，並討論它與 B型肝炎之關係。
關鍵字
無資料並列摘要
Gianott's disease (popular acrodermatitis of childhood), which occurs especially in young children, consists of crops of nonpruritic papules, lymphadenopathy and acute anicteric hepatitis with the presence of hepatitis B surface antigen (HBsAg). We are reporting the first case of Gianotti's disease in Taiwan. The patient was a 14-month-old boy who had symmetrical, nonpruritic popular skin eruptions over the face, extremities and buttocks. Lymphadenopathy was also noted in the cervical and inguinal regions. Laboratory tests disclosed positive HBsAg and elevation of serum aminotransferases at the onset of the disease. Three months later, HBsAg became negative, anti-HBc became positive and anti-HBs became negative. Possible role of hepatitis B virus infection in Gianotti's disease is discussed.
延伸閱讀
- Lee, H. C. (2007). 兒童急性A型肝炎. Acta Paediatrica Taiwanica, 48(3), 105-106. https://doi.org/10.7097/APT.200706.0105
- 文萬欣（2013）。接種B型肝炎疫苗兒童發生B型肝炎病毒感染之研究〔博士論文，國立臺灣大學〕。華藝線上圖書館。https://doi.org/10.6342/NTU.2013.01412
- 許宏遠（2008）。兒童慢性B型肝炎之處置。臺灣消化醫學雜誌，25()，94-96。https://www.airitilibrary.com/Article/Detail?DocID=10137696-200806-201507220001-201507220001-94-96
- 吳志峰、胡克信、陳坤南、馮天民（2002）。Adult-Onset Still's Disease - Case Report。中華民國耳鼻喉科醫學雜誌，37(4)，288-291。https://doi.org/10.6286/2002.37.4.288
- Tsou, K. I., & Chen, C. H. (1976). A Case Report of Bartter's Syndrome. Acta Paediatrica Sinica, 17(2), 79-89. https://www.airitilibrary.com/Article/Detail?DocID=00016578-197606-17-2-79-89-a