A Comparative Study Nuclear Angiocardiography and Fick Method in Determination of Pulmonary-To-Systemic Blood Flow Ratio

核子醫學心臓血管攝影檢查，是一種非侵犯性、快速、低輻射劑量且可重覆檢查的技術。因此，目前被廣泛應用於心臟血管疾病的診斷。此法是經由靜脈快速注射放射性同位素，再分析此放射性物質流經肺之濃度時間曲線，即可精確地計算出左至右分流量之比率。本文的目的在於分析核子醫學心臟血管攝影及心導管檢查氧氣分析法兩者，應用於測定心臟血管系統左至右分流量的相關性。自1983年12月起至1984年8月止，共計有62位病童接受核子醫學心臟血管攝影檢查。平均年齡4.9歲（年齡分佈為8個月至13歲），男性33位，女性29位。每位患童接受兩種檢查相隔的時間為1至4天。根據研究結果，發現二法間具有良好的相關性。尤其在右肺所測定的左至右分流量與心導管檢查Fick法計算值比較，更是理想，r值為0.98。

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並列摘要

Radionuclide techniques are of growing importance in the field of diagnostic cardiology. First-pass nuclear angiocardiography (FPNA) is a rapid, non-invasive, low radiation dose procedure that yields accurate and reproducible measurements of left-to-right cardiac shunts. The most recent method consists of recording of a first pass through the lung and the determination of the pulmonary-to-systemic flow ratio (Qp/Qs) by using a gamma-function fit. This has proved to be accurate when the tracer is delivered as a quick, discrete bolus. This study was designed to consider correlative relationships between FPNA and Fick methods in the detection and quantitanton of left-to-right shunts. From December 1983 to August 1984, a total of 72 FFNA with Tc-99m (Sn) albumin were performed in 62 infants and children whose ages ranged from 8 months to 13 years, with a mean age of 4.9 years. Twenty-nine of them were female; thirty-three were male. The oxygen saturation was estimated by using an American Optical Company microoximeter during cardiac catheterization. The size of left-to-right shunt was measured by the Fick method. The FPNA were performed within one to four days of catheterization. The result of our study showed good correlation between FPNA and cardiac catheterization, especially the Qp/Qs derived by C2/C1 ratio method with the region of interest at the right lung (r=0.98).

並列關鍵字

first-pass nunclear angiocardiography ； lefl-to-rlght shunts

國際替代計量

A Comparative Study Nuclear Angiocardiography and Fick Method in Determination of Pulmonary-To-Systemic Blood Flow Ratio

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