Respiratory Syncytial Virus and Bronchiolitis

呼吸合成病毒與細小支氣管炎

Richard J. Lemen

《Acta Paediatrica Sinica》 36卷2期 (1995/04) Pp. 78-85

https://doi.org/10.7097/APS.199504.0078

並列摘要

Viral bronchiolitis is a common world-wide disease of infants and children resulting in respiratory failure and occasionally death. The major underlying pathophysiology is airway inflammation of peripheral airways and airway hyperresponsiveness to bronchoprovocation. Management is primarily prevention through strict hand washing and avoidance of exposures during respiratory seasons, especially in small infants who have underlying heart or lung disease. Careful supportive therapy, including fluid hydration, good nutrition, and aerosolized bronchodilators, steroids or ribavirin may be helpful. Long term follow-up for these children is important because a significant number will have recurrent episodes of bronchiolitis and wheezing, and many will develop clinical asthma. There's some evidence that long term abnormalities of airway function, perhaps secondary to airway fibrosis, may result from bronchiolitis infections. Avoidance of exposure to passive smoking, cold air and air pollutants is also beneficial to long term recovery from RSV bronchiolitis. Passive immunization against RSV may be possible in the near future.

並列關鍵字

Bronchiolitis ； respiratory syncytial virus ； lung injury ； inflammation ； children