When genetically modified (GM) crops cross with cultivars, wild relatives, and weeds, great impacts on natural environment and biodiversity may arise. Rice is one of the most important crops in the world, providing a staple food for over half of the global population. There are many GM rice have been successfully bred, such as herbicide tolerance, disease resistance, insect resistance, salt tolerance, drought tolerance, high protein content, and high yield. Although rice is a self-pollinated crop, its transgenes can result in gene flow through the pollen flow. In this review paper, we discuss the factors of pollen-mediated gene flow in rice, and introduce the model to simulate the dispersion of GM rice pollen to the non-GM rice and the maximum distance of pollen flow can be predicted. The information can be the reference for coexistence between GM and non-GM rice.