Bullous Eruptions Caused by Extravasation of Mannitol-A Case Report

Mannitol外滲引起大水泡之病例報告

張國安(Kow-Aung Chang) ； 姚文聲(Bruno Jawan) ； 陸翔寧(Hsiang-Ning Luk) ； 馮仕端(Si-Tun Fung) ； 李汝浩(Ju-Hao Lee)

《Acta Anaesthesiologica Sinica》 39卷4期 (2001/12) Pp. 195-198

https://doi.org/10.6955/AAS.200112.0195

摘要

靜脈注射液外滲在麻醉中常會遇到，在此，我們報告一件罕見案例。病患因腦部手術麻醉中，接受mannitol靜脈注射而外滲引起手背及前臂之多處水泡病變。此乃因mannitol之高滲透壓所致。將患部舉高並以silver sulfadiazine每日敷兩次，使水泡在十天後全部消失。早期診斷及治療爲成功恢複正常之關健，文中將描述整個過程並討論應採取之預防措施。

關鍵字

Mannitol ； 藥物疹 ； 手術後併發症：外滲

並列摘要

Extravasation is one of the common complications seen with intravenous infusion. We bring forward a case of subcutaneous mannitolextravasation, which caused swelling and multiple cutaneous bullous eruptions in the hand and forearm during craniotomy. Treatment consisting of elevation of the affected extremity and application of silver sulfadiazine ointment twice daily to the injured area was successful. The possible mechanisms relevant to extravasation and its tissue damage are reviewed and discussed. Selecting properintravenous infusion site, using pliable catheters and frequent inspection are important steps for prevention of extravasation.

並列關鍵字

Mannitol ； Drug eruptions ； Post operative complication: extravacation