八十八年下半年及八十九年度調製劑中藥檢出西藥情形之分析

Survey on Adulterants in Prescriptive Chinese Herbal Medicines from 1999 to 2000

林美智(Mei-Chih Lin) ； 劉宜祝(Yi-Chu Liu) ； 溫國慶(Kuo-Ching Wen) ； 林哲輝(Jer-Huei Lin) ； 廖俊亨(Chun-Heng Liao)

《藥物食品檢驗局調查研究年報》 19號 (2001/09) Pp. 182-195

https://doi.org/10.6946/ASRNL.200109.0182

摘要

本報告係本局於八十八年七月至八十九年十二月間受理衛生行政機關、司法檢警情治機關送驗調製劑中藥摻加西藥案件，計843件之統計分析。結果如次，受理之調製劑中藥摻加西藥屬消費者申訴及司法檢警情治機關之服務案件者，其檢出率為18.1%。涵蓋衛生行政機關抽查案件則檢出率為15.1%。檢體來源屬合法廠商、醫療機構之調製劑中藥摻加西藥之平均檢出率8.5%。屬依法不得販售、提供藥品者其平均檢出率23.5%，以國術館檢出率最高。分析120件不合格檢體中，每件檢體檢出西藥個數以檢出一種西藥成分最多，佔17.5%，其次檢出五種西藥成分佔15.0%，檢出二種及七種西藥成分均佔12.5%。檢出西藥之120件檢體依劑型別，膠囊劑檢出率最高，佔27.9%。檢出西藥檢體依送驗指定主治效能排名，前三名依序為風濕鎮痛類、類因醇類及感冒鎮咳類，然檢出之西藥成分常與指定效能或指定之檢驗成分無關。西藥成分之檢出頻率依序為caffeine，thiamine，diazepam，hydrochlorothiazide，acetaminophen，indomethacin，ethoxybenzamide，chlorpheniramine，chlorzoxazone，dicyclomine及ibuprofen。

關鍵字

中藥摻加西藥 ； 風濕鎮痛類 ； 類固醇類 ； 感冒鎖咳類

並列摘要

In this study, we present the result on the synthetic chemicals contained, as adulterants, in 843 samples of Chinese herbal medicine, which we collected and analyzed from 1999 to 2000. The result indicates that 18.1% of the samples obtained from the consumer centers of the local health bureaus are adulterated. However, if we include the samples that are randomly taken from local markets by the health bureau officers, the adulteration rate decreases to 15.1%.
In the first category, which the supply sources includes legal manufacturers of Chinese herbal medicine and medical units (hospitals and clinics of traditional Chinese medicine), approximately 0-22.2% of the samples are adulterated. In the second category, which includes Chinese Kung-fu stores, folk medicine stores, unlicensed practitioners and others, the adulterations rate ranges from 17.5 to 43.1%. Among them, the Kung-fu stores have the highest rate of adulteration.
While the average number of adulterants in each sample is 4.4, there are as high as 17.5% of the samples contain one type of adulterants, and about 15% contain five types. In terms of categories and forms of dosage, the common found adulterants are antirheumatic-analegesics, steroids, anticold-antitussives; the forms of dosage include capsule (27.5%), pill (13.8%) and powder (13.1%). In terms of regions, the rates of adulterations found are: in special municipalities (18.2%), in towns (15.9%), in counties (15.5%), and in provincial cities (8.4%).
Adulterants found in the Chinese herbal medicine are not only associated with the required categories as indicated above. Other adulterants found are, as ranked by the frequency of use: caffeine, thiamine, diazepam, hydrochlorothiazide, acetaminophen, indomethacin, ethoxybenzamide, chlorpheniramine, chlorzoxazone, dicyclomine and ibuprofen.

並列關鍵字

Adulterants in Prescriptive Chinese Herbal Medicines