The Correlation between Nasal Eosinophilia and the Allergic Appearance of Nasal Mucosa

鼻腔嗜伊紅性白血球增多與鼻黏膜過敏性之關係

蔡肇基(Jaw-Ji Tsai) ； 林清榮(Chin-Zon Lin) ； 張斌(Ping Chang) ； 王世叡(Soo-Ray Wang)

《The Kaohsiung Journal of Medical Sciences》 2卷10期 (1986/10) Pp. 635-638

https://doi.org/10.6452/KJMS.198610.0635

摘要

在鼻科門診臨床診斷為過敏性鼻炎之62名病人中，研究鼻腔與血中之嗜伊紅性白血球數量、血清中IgE值及其間相互之關係。鼻腔分泌物檢體之取法有二：group 1 (n=22)抹取兩邊鼻腔之分泌物，group 2 (n=44)則刮取兩邊鼻腔之黏膜，group 1 有4片 (4/44)檢體不足，而group 2 則沒有不足之現象 (0/88)。
當只檢查一邊鼻腔時，有四例 (4/62)為偽陰性，三例來自group 1，一例來自group 2。嗜伊紅性白血球在鼻腔之增多與血中之增多具有好之相關性(p＜0.001)，前者與血清IgE值之升高亦具有相關性(p＜0.05)。
這些病人之中，48% (32/62)血中之嗜伊紅性白血球數目偏高，36% (21/59)血清中IgE值偏高，但鼻腔嗜伊紅性白血球數目偏高者高達69%。
由本實驗之結果，建議鼻腔抹片應列為例行檢驗，它既簡單又經濟。當鼻腔檢體不足時，應改用刮匙來刮取檢體，而不用棉棒抹取。

並列摘要

Sixty two patients with a clinical diagnosis of nasal allergy in a rhinology clinic were studied for nasal eosinophil grades, blood eosinophil counts, and serum IgE levels. Two methods of nasal sampling were used, swabbing (group 1, n=22) and scratching (group 2, n=44) were carried out to both sides of the nasal cavities. Four samples (4/44) were inadequate in group 1, and none (0/80) in group 2.
Examination of just one cavity would have resulted in a false negative in four cases (4/62), three from group 1 and one from group 2. The results indicated a good correlation of nasal eosinophilia with blood eosinophil counts (p＜0.001) and with serum IgE levels (p＜0.05).
Forty-eight percent (30/62) of patients had high blood eosinophil counts, and 36% (21/59) had high serum IgE levels, while 69% (43/62) had positive nasal eosinophilia. It is advised that nasal smears should be routinely examined since it is simple and not expensive. When the nasal sample is inadequate in quantity, scratching with a plasic scraper, instead of swabbing with a cotton swab, is preferred.

並列關鍵字

nasal allergy ； nasal and blood eosinophils ； serum IgE