- 期刊
Evaluation of Retinal Nerve Fiber Layer Thickness in Diabetic Retinopathy after Panretinal Photocoagulation
糖尿病視網膜病變經全網膜雷射凝固治療後視網膜神經纖維層厚度之評估
摘要
以神經纖維分析儀分析神經纖維層厚度已應用於許多眼疾。本研究用掃描式雷射偏極儀測量27例糖尿病視網膜病變，經全網膜雷射凝固治療後，其視網膜神經纖維層之厚度變化。評估的參數包括對稱性、神經纖維層橢圓單位組成、橢圓均值、平均厚度，變化數值、以及上、下、鼻、顳側的平均神經纖維層厚度、並計算上下神經纖維層與顳側及鼻側神經纖維層之相對比值。結果顯示，對稱性、神經纖維層橢圓單位組成、橢圓均值、平均厚度及變化數值分別為0.90、1.80、63.6、63.0及45.8μm。上、下、鼻、顳側的平均神經纖維層厚度分別為65.8、75.1、44.47及38.78μm。若以顳側值為參考，上下側對顳側之比值分別為1.77及2.00。若以鼻側值為參考，上下側對鼻測之比值分別為1.51及1.72。本研究顯示，視網膜水腫不會增加糖尿病視網膜病變患者的神經纖維層厚度，且上下神經纖維層與顳側的相對比值，在神經纖維分析儀對於糖尿病視網膜病變，經全網膜雷射凝固治療後神經纖的評估上，較上下神經纖層與鼻側的相對比值更有意義。
並列摘要
Retinal nerve fiber layer (RNFL) thickness analysis has been used in glaucoma and some other ocular diseases. In this study, we measured RNFL thickness using scanning laser polarimetry in 27 eyes with diabetic retinopathy after panretinal photocoagulation (PRP). Symmetry, ellipse modulation, ellipse average, average thickness, number (a measure of RNFL change), and superior, inferior, nasal, and temporal average RNFL thicknesses were measured. Mean symmetry was 0.90, mean ellipse modulation 1.80, mean ellipse average 63.6 μm, mean average thickness 63.0μm, and mean number 45.8. Average superior RNFL was 65.8μm, average inferior RNFL 75.1μm, average nasal RNFL 44.47 μm, and average 63.6μm, mean average thickness 63.0μm, and mean number 45.8. Average superior RNFL was 65.8 μm, average inferior RNFL 75.1μm, average nasal RNFL 44.47μm, and average temporal RNFL 38.78μm. The superior / temporal and inferior / temporal ratios were 1.77 and 2.00, respectively; superior / nasal and inferior / nasal ratios were 1.51 and 1.72, respectively. Retinal edema did not increase laser retardation. The superior / temporal and inferior / temporal ratios were more reliable in evaluating nerve fiber analyzer data in patients with diabetic retinopathy after PRP.
延伸閱讀
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