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Intravascular Lymphomatosis Mimicking Acute Disseminated Encephalomyelitis: A Case Report

血管內淋巴瘤類似急性播散性腦脊髓炎表現-病例報告

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摘要


我們報告一例49歲女性診斷為血管內淋巴瘤之臨床表現、放射線學檢查及解剖所見。本病人以進行性四肢無力之後續發成播散性大腦神經症狀,生前的臨床及放射線檢查診斷為擴散性脊髓炎,給予類固醇脈波治療和靜脈內免疫球蛋白注射,但並未有反應。三個月後死於多重器官衰竭,解剖標本以組識病理及免疫組識化學染色證實為血管內大型B細胞淋巴瘤。

並列摘要


We describe the clinical, radiologic, and postmortem findings in a 49-year-old woman with intravascular lymphomatosis. The patient presented with progressive limb weakness followed by progressive disseminated cerebral neurologic symptoms. Disseminated encephalomyelitis was suspected due to the clinical and radiologic findings. Steroid pulse therapy and intravenous immunoglobulin were given but did not help. The patient died of multiple organ failure 3 months after the onset of symptoms. A diagnosis of disseminated intravascular large B-cell lymphomatosis was established based on findings from histopathology and immunohistochemistry studies on autopsy specimens of the brain and other visceral organs collected postmortem.

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