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Unusual Solitary Fibrous Tumors in the Central Nervous System: A Report of Two Cases

罕見的中樞神經系統單獨纖維瘤-兩個病例報告

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摘要


單獨纖維瘤是少見的腫瘤,大部分發生於肋膜。肋膜外的單獨纖維瘤罕見,發生部位包括肺、心包膜、縱膈腔、任何地方的軟組織、上呼吸道,發生於中樞神經系統的單獨纖維瘤是新的名詞,其生物特質目前未明,從臨床上瞭解不多,即使現在,大部分的神經外科醫師還是很難接受這種診斷。臨床表現上大部分是良性,追蹤後發生復發的案例極少,但仍有文獻報告過惡性轉變或轉移的病例。故所有的單獨纖維瘤應該視爲有惡性轉變的可能,要長期追蹤。我們報告兩個罕見的中樞神經系統單獨纖維瘤,讓臨床醫師瞭解這種不同於其他中樞神經系統的腫瘤。

並列摘要


Solitary fibrous tumors (SFT5) are uncommon, and most are found in the pleura. Extrapleural SFTs are rare and have been found in the lung, pericardium, mediastinum, soft tissue of any site, and upper respiratory tract. SFTs of the central nervous system (CNS) are very rare. The biologic features are unknown and remain poorly understood from a clinical standpoint. Most neurosurgeons do not believe that SFTs can present as primary CNS neoplasms. Most SFTs are clinically benign and indolent, and recurrences after surgical excision are scarce. Because malignant transformation or metastasis has been reported, all SFTs should be treated as having malignant potential. Long-term follow-up is recommended. We report two cases, so that surgeons may recognize that this is an entity different from other spindle-cell CNS tumors.

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