The Role of Different Portions of Lower Brain Stem of the Cat in the Central Cardiovascular Control Mechanism

下腦干腹背左右間的相互關系

蔡作雍(C. Y. Chai)

《The Chinese Journal of Physiology》 19卷1期 (1963/06) Pp. 55-64

摘要

用42隻去大腦，切斷迷走神經，胸腔打開的貓，分別刺激下腦幹背部或腹部等，研究所引起的血壓升高，心收縮增強，與心摶率增快等反應。將下腦幹背部或整個下腦幹從中線切開分為左右兩半，血壓，心收縮力，與心摶率均不現嚴重的改變。將下腦幹一側背部除去後，血壓，心收縮力與心摶率均低減，刺激同側的腹及其側部所引起的反應降低更為明顯。反之切去他側背部，血壓，心收縮力與心摶率雖降低，但用相同的刺激，則不會引起該腹及其側部起進一步的低減。故此結果支援中樞性心臟血管控制機構是在下腦幹部的學說。而下腦幹背部左右兩側間，大體上是獨立的，下腦幹各部傳遞心臟血管的控制作用是循同側而不交叉的神經纖維向下傳的。

並列摘要

The functional relationship between different portions of the lower brain stem in reference to the pressor, cardioaugmentor, and cardioaccelertor responses resulting from electrical activation was studied on 42 vagotomized, midcollicular decerbrate, open-chest cats. Complete longitudinal division of the right and left dorsal portions and complete longitudinal bisection of the lower brainstem affected the basal vasomotor and cardiac conditions and their responses insignificantly. Ablation of the ipsilateral dorsal portion diminished the basal cardiovascular conditions and their responses markedly and significantly on stimulation of the ventral and ventrolateral portion, while ablation of the contralateral dorsal portion failed to diminish the same responses significantly. These observations support the previous finding that the central cardiovascular control mechanism resides in the dorsal portion of the lower brain stem. Furthermore, the dorsal portion of the one side functions essentially independently from that of the other, and the fibers of various portion of the lower brain stem responsible for central cardiovascular control mechanism descends predominantly homolaterally.