採用已成長之鼠比較經下視丘背中核兩側破壞前後之食量及飲水量,並由固定胃管注射植物油以觀察食量代償之狀況。結果發現下視丘背中核之破壞造成飲水量之顯著減少,而食量雖亦有減少但未達統計意義。植物油之胃內注射使所有三組動物,包括正常對照、手術失誤以及背中核破壞等,均發生顯著食量減低,但代償並不完全,而各組之間亦無顯著差異。
Ingestive compensation to additional calories was studied in adult rats bearing bilateral lesions in the dorsomedial hypothalamic nucleus. Each animal was equipped a transperitoneal gastric fistula to facilitate intubation of a vegetable oil. It was found that animals of the intact control, target missed, and dorsomedially lesioned groups all reduced oral food intake during the period of fat intubation but the compensation was only partial and was not significantly different among groups. The dorsomedial lesions caused significant hypodipsia but not hypophagia in this small sample.