- 期刊
Social Isolation during Peri-Adolescence or Adulthood: Effects on Sexual Motivation, Testosterone and Corticosterone Response under Conditions of Sexual Arousal in Male Rats
並列摘要
Reproductive functions in adult organism are known to be affected by different factors. Effects of social environment at the postnatal ontogenesis attract particular attention since it has deep impact on the development of physiological and emotional state of an individual. Effects of chronic social isolation at different ages on male sexual motivation, testosterone and corticosterone response under conditions of sexual arousal were studied in Wistar rats. After weaning at 21 day of age, rats of one group were isolated for six weeks and after that they were housed in groups of five per cage for ten weeks (Iso3-9). Rats of the second group were housed in groups of five animals per cage till 13 weeks of age, and then they were isolated for six weeks (Iso13-19). Rats of the control group were housed in groups during the experiment. Adult 19 week-old male rats were tested under conditions of sexual arousal. The expression of sexual motivation was estimated as the behavioral activity of a male at the transparent perforated partition separating a receptive female. Isolation of adult male rats reduced the number of approaches to the partition, while the period of time a male spent at the partition was not changed and testosterone response was enhanced as compared to control rats. Chronic social isolation during peri-adolescence reduced sexual motivation and prevented arousal-induced elevation of testosterone. Plasma corticosterone increases at sexual arousal in the two groups of isolated rats did not differ from that in controls. Our results are evidence that social isolation during the post-maturity stage (Iso13-19) did not diminish the manifestation of sexual motivation and hormonal response to a receptive female, while isolation during peri-adolescence attenuated behavioral and hormonal expression of sexual arousal in adult males.
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- Yunes, R., Casas, S., Gaglio, E., & Cabrera, R. (2015). Progesterone Exerts a Neuromodulatory Effect on Turning Behavior of Hemiparkinsonian Male Rats: Expression of 3α-Hydroxysteroid Oxidoreductase and Allopregnanolone as Suggestive of GABA_A Receptors Involvement. Parkinson＇s Disease, 2015(), 277-285. https://doi.org/10.1155/2015/431690
- 周聖夏（2013）。Effects of docosahexaenoic acid deficiency on stress-induced glucocorticoid secretion in adult male rats〔碩士論文，國立臺灣大學〕。華藝線上圖書館。https://doi.org/10.6342/NTU.2013.02238
- Sircar, R., & Ishiwari, K. (2014). Systemic Administration of γ-Hydroxybutyric Acid in Adolescent Rat Impairs Contextual Fear Conditioning, But Not Cued Conditioning. Journal of Drug and Alcohol Research, (3), c1-8. https://doi.org/10.4303/jdar/235801
- 孫玉滿、何美泠、許勝光、彭明聰（1993）。The Effects of Neonatal Monosodium Glutamate Treatment on Sex-odor Attractivity and Approach Behavior in Rats。The Kaohsiung Journal of Medical Sciences，9(4)，232-242。https://doi.org/10.6452/KJMS.199304.0232
- Lau, W. M. (2009). Study of adult neurogenesis and molecular mechanism underlying sexual behavior in male rats following induction of depression-like behaviorand pharmacological treatment [doctoral dissertation, The University of Hong Kong]. Airiti Library. https://www.airitilibrary.com/Article/Detail?DocID=U0029-1812201200015243