Effects of Vitamin D Fortified Milk on Vitamin D Status in Mongolian School Age Children

維生素D強化牛奶對蒙古學齡兒童微生素D狀態之效應

Davaasambuu Ganmaa ； Uush Tserendolgor ； Lindsay Frazier ； Erika Nakamoto ； Nyamjav Jargalsaikhan ； Janet Rich-Edwards

《Asia Pacific Journal of Clinical Nutrition》 17卷1期 (2008/03) Pp. 68-71

https://doi.org/10.6133/apjcn.2008.17.1.11

摘要

居處在北方高緯度而冬季鮮能接受到UV-B紫外線的照射，以及難以獲得有維生素D強化的食物，使得蒙古人成為缺乏維生素D的高危險群。我們在2005年5月進行一個先驅研究來估計蒙古學齡兒童中低維生素D的盛行率，並且評估實施一個較長期也較具規模以強化牛奶和維生素D補充劑試驗的可行性。46位9－11歲的蒙古兒童（22位女孩，24位男孩），76％（35位）其25-羥基維生素D低於50nmol/L（20ng/mL），32％低於37nmol/L（15ng/mL）。在每日食用添加維生素D的牛奶710mL（共300IU或7.5μg）一個月後，只有3個兒童低於50nmol/L（20ng/mL）、沒有人低於37nmol/L（15ng/mL）。這些結果顯示蒙古青春期前學齡兒童有嚴重的25（OH）D缺乏，可以飲用添加約7.5μg維生素D3的牛奶一個月來改善。

關鍵字

牛奶 ； 維生素D缺乏 ； 生長 ； 軟骨症 ； 蒙古

並列摘要

Mongolians are at high risk for vitamin D deficiency because of their residence at northern latitude, reduced exposure to UV-B rays during the winter months, and a low availability of vitamin-D fortified foods. We performed a pilot study in May 2005 to estimate the prevalence of hypovitaminosis D in Mongolian school age children and to determine the feasibility of conducting a longer and larger trial with fortified milk and vitamin D supplements. In a group of 46 Mongolian children (22 girls and 24 boys) aged 9-11 years, 76% (35) had levels of 25-hydroxyvitamin D (25(OH)D) below 50nmol/L (20ng/mL) and 32% had levels below 37nmol/L (15ng/mL). After a month of consuming 710 ml of vitamin D-fortified (total 300IU or 7.5μg) milk daily, only 3 of the children were below 50nmol/L (20ng/mL) and none below 37nmol/L (15ng/mL). These results reveal prevalent and serious 25(OH)D deficiency among Mongolian prepubertal school age children that appears to be ameliorated by a month of consuming approximately 7.5μg of vitamin D3 in fortified milk.

並列關鍵字

milk ； vitamin D deficiency ； growth ； rickets ； Mongolia