Iodine Status and Thyroid Function of Pregnant, Lactating Women and Infants (0-1 Yr) Residing in Areas with an Effective Universal Salt Iodization Program

食盐加碘措施有效落实地区孕妇、哺乳期妇女及婴儿碘营养和甲状腺功能

Yan-Ling Wang ； Zhong-Liang Zhang ； Peng-Fei Ge ； Yi-Bo Wang ； Shi-Gong Wang

《Asia Pacific Journal of Clinical Nutrition》 18卷1期 (2009/03) Pp. 34-40

https://doi.org/10.6133/apjcn.2009.18.1.06

摘要

Objective: To assess the iodine nutrition and thyroid function of pregnant women, lactating women and infants residing in areas where the Universal Salt Iodization program is in place. Methods: Pregnant women, lactating women and infants were selected randomly in the regions where iodized salt coverage rate is more than 90% since 2000. Urine iodine levels of pregnant woman, lactating woman and infants, milk iodine of lactating woman, thyroid-stimulating hormone (TSH) and free T4 of women were tested respectively. Results: Median Urinary Iodine (MUI) of infants, three groups of pregnant women (first, second and third trimester) and two groups lactating women (breastfeeding less than or more than six months) were 233, 174, 180, 147, 126 and 145 μg/L, respectively. Median milk iodine of lactating women was 163 μg/L. Percentage of milk iodine ＜ 150 μg/L of early lactating women was 40% less than that of late lactating women (p ＜ 0.01).There was a positive correlation between urine iodine of infants and milk iodine of lactating women (r = 0.526, p = 0.000). T4 of two women were above or below the reference range. Total 15.4% women's TSH were abnormal. Most of these women’s urinary iodine were lower than 150 μg/L. Conclusion: Iodine status of most of the target population for Universal Salt Iodization program is adequate, but iodine deficiency still existed in some. To assure every new life’s brain not be damaged by iodine deficiency, iodine status of targeted populations should be monitored and supplements provided according to the monitoring outcomes.

關鍵字

碘营养 ； 碘盐 ； 甲状腺激素 ； 尿碘 ； 乳碘

並列摘要

Objective: To assess the iodine nutrition and thyroid function of pregnant women, lactating women and infants residing in areas where the Universal Salt Iodization program is in place. Methods: Pregnant women, lactating women and infants were selected randomly in the regions where iodized salt coverage rate is more than 90% since 2000. Urine iodine levels of pregnant woman, lactating woman and infants, milk iodine of lactating woman, thyroid-stimulating hormone (TSH) and free T4 of women were tested respectively. Results: Median Urinary Iodine (MUI) of infants, three groups of pregnant women (first, second and third trimester) and two groups lactating women (breastfeeding less than or more than six months) were 233, 174, 180, 147, 126 and 145 μg/L, respectively. Median milk iodine of lactating women was 163 μg/L. Percentage of milk iodine ＜ 150 μg/L of early lactating women was 40% less than that of late lactating women (p ＜ 0.01).There was a positive correlation between urine iodine of infants and milk iodine of lactating women (r = 0.526, p = 0.000). T4 of two women were above or below the reference range. Total 15.4% women's TSH were abnormal. Most of these women’s urinary iodine were lower than 150 μg/L. Conclusion: Iodine status of most of the target population for Universal Salt Iodization program is adequate, but iodine deficiency still existed in some. To assure every new life’s brain not be damaged by iodine deficiency, iodine status of targeted populations should be monitored and supplements provided according to the monitoring outcomes.

並列關鍵字

iodine nutrition ； iodized salt ； thyroid hormone ； urine iodine concentration ； milk iodine concentration