Maternal and Neonatal Plasma N-3 and N-6 Fatty Acids of Pregnant Women and Neonates from Three Regions of China with Contrasting Dietary Patterns

中国三个不同膳食模式地区孕妇及新生儿血浆n-3和n-6系列脂肪酸水平

Jian Zhang ； Yi-Qun Wang ； Li-Ping Meng ； Chun-Rong Wang ； Wen-Hua Zhao ； Jun-Shi Chen ； Kebreab Ghebremeskel ； Michael A Crawford

《Asia Pacific Journal of Clinical Nutrition》 18卷3期 (2009/09) Pp. 377-388

https://doi.org/10.6133/apjcn.2009.18.3.10

摘要

The aim of this study was to investigate n-3 and n-6 fatty acid status of pregnant women and neonates from River/Lake, Coastal and Inland regions of China. Demographic, nutritional and anthropometric data, as well as blood samples (maternal and cord) were obtained. Plasma choline phosphoglyceride (CPG) fatty acids were analysed. Median daily fatty acid intakes of the women from River/Lake, Coastal and Inland women were linoleic acid (LA), 20.2, 22.1, 31.7 g; arachidonic acid (AA), 157.2, 95.6, 141.3 mg; α-linolenic acid (ALA), 4.2, 1.0, 1.8 g; eicosapentenoic acid (EPA), 22.4, 28.6, 3.1 mg; docosahexaenoic acid (DHA), 51.7, 54.7, 33.3 mg and the n-6 to n-3 fatty acid ratio, 4.7, 20.9, 17.2. The median maternal and cord plasma CPG AA levels of River/Lake, Coastal and Inland groups were 7.3% and 15.7%, 6.7% and 16.1%, and 7.2% and 16.9%. The median maternal and neonatal DHA levels in the three regions were 3.2% and 4.7%, 3.0% and 4.3%, and 2.0% and 3.6%. There appears to be a close association between dietary intake of AA, EPA, DHA and the corresponding levels of the fatty acids in maternal plasma CPG (p＜0.05). The results of the study indicate low intake of the n-3 long chain polyunsaturated fatty acids, EPA and DHA, and n-6 to n-3 fatty acid imbalance are the main problems of dietary fat intake of Chinese pregnant women. Measures such as increased supply of oily fish and ALA-rich edible oils should be taken to help enhance n-3 fatty acid intake of pregnant Chinese women.

關鍵字

二十二碳六烯酸 ； 花生四烯酸 ； 二十碳五烯酸 ； 中国孕妇 ； 新生儿

並列摘要

The aim of this study was to investigate n-3 and n-6 fatty acid status of pregnant women and neonates from River/Lake, Coastal and Inland regions of China. Demographic, nutritional and anthropometric data, as well as blood samples (maternal and cord) were obtained. Plasma choline phosphoglyceride (CPG) fatty acids were analysed. Median daily fatty acid intakes of the women from River/Lake, Coastal and Inland women were linoleic acid (LA), 20.2, 22.1, 31.7 g; arachidonic acid (AA), 157.2, 95.6, 141.3 mg; α-linolenic acid (ALA), 4.2, 1.0, 1.8 g; eicosapentenoic acid (EPA), 22.4, 28.6, 3.1 mg; docosahexaenoic acid (DHA), 51.7, 54.7, 33.3 mg and the n-6 to n-3 fatty acid ratio, 4.7, 20.9, 17.2. The median maternal and cord plasma CPG AA levels of River/Lake, Coastal and Inland groups were 7.3% and 15.7%, 6.7% and 16.1%, and 7.2% and 16.9%. The median maternal and neonatal DHA levels in the three regions were 3.2% and 4.7%, 3.0% and 4.3%, and 2.0% and 3.6%. There appears to be a close association between dietary intake of AA, EPA, DHA and the corresponding levels of the fatty acids in maternal plasma CPG (p＜0.05). The results of the study indicate low intake of the n-3 long chain polyunsaturated fatty acids, EPA and DHA, and n-6 to n-3 fatty acid imbalance are the main problems of dietary fat intake of Chinese pregnant women. Measures such as increased supply of oily fish and ALA-rich edible oils should be taken to help enhance n-3 fatty acid intake of pregnant Chinese women.

並列關鍵字

docosahexaenoic acid ； arachidonic acid ； eicosapentenoic acid ； Chinese pregnant women ； neonate