Veganism does not Reduce the Risk of the Metabolic Syndrome in a Taiwanese Cohort

纯素食没有降低代谢综合症的发病风险－台湾队列研究

Peng-Hui Shang ； Zheng Shu ； Yan-Fang Wang ； Na Li ； Song-Ming Du ； Feng Sun ； Yin-Yin Xia ； Si-Yan Zhan

《Asia Pacific Journal of Clinical Nutrition》 20卷3期 (2011/09) Pp. 404-410

https://doi.org/10.6133/apjcn.2011.20.3.07

摘要

本研究的目的是为了比较台湾人群纯素食者相对鱼类素食、蛋奶素食和非素食者代谢综合症的发病风险。采用回顾性队列的研究方法，采集台湾美兆集团1996-2006年期间的健康体检数据进行二手数据分析。共有93,209名健康体检者纳入研究对象，根据自我调查问卷中的食物摄取频率表，将其分为纯素食、鱼类素食、蛋奶素食和非素食者四种类型。采用COX比例风险模型，分析不同膳食分组者发生代谢综合症和代谢综合症组分的风险。在平均3.75年的观察期内，总共有8006个代谢综合症新发病例，发生率为229（95% CI, 224, 234）/10000人年。控制性别、年龄、教育程度、吸烟、饮酒、工作勞動、休閒运动等混杂因素的影响后，与纯素食者相比，非素食、鱼类素食和蛋奶素食者代谢综合症发生危险比（HR）分别为0.75（95% CI, 0.64, 0.88）, 0.68（95% CI, 0.55,0.83）和 0.81 （95% CI, 0.67, 0.97）。代谢综合症组分发病风险的分析结果显示，与纯素食者相比，非素食和鱼类素食者低的高密度脂蛋白胆固醇发生的HR分别为0.72（95% CI, 0.62, 0.84）和0.70（95% CI, 0.57, 0.84），非素食者高空腹血糖发生的HR为1.16 （95% CI, 1.02, 1.32）。我们的研究结果提示：相对于鱼类素食、蛋奶素食和非素食者而言，纯素食没有降低代谢综合症的发病风险。

關鍵字

纯素食 ； 鱼类素食 ； 蛋奶素食 ； 非素食 ； 代谢综合症

並列摘要

The purpose of the present study was to assess the risk of the metabolic syndrome (MS) with vegan, pescovegetarian, lactovegetarian and nonvegetarian diets in Taiwan. The design was a retrospective cohort study using secondary data analysis from a Taiwan longitudinal health check-up database provided by MJ Health Screening Center during 1996-2006. A total of 93209 participants were classified as vegans (n=1116), pescovegetarians (n=2461), lactovegetarians (n=4313) and nonvegetarians (n=85319) by food frequency list of self-administered questionnaire at baseline. The association between MS or MS components and different dietary groups was evaluated using Cox proportional-hazards regression models with adjustment for confounders. During the mean 3.75 years of follow up, a total 8006 MS incident cases occurred and the incidence of MS was 229 (95% CI, 224, 234) per 10000 person year. Compared with vegans, hazard ratios of MS for nonvegetarians, pescovegetarians, lactovegetarians were 0.75 (95% CI, 0.64, 0.88), 0.68 (95% CI, 0.55, 0.83) and 0.81 (95% CI, 0.67, 0.97) after adjusting for sex, age, education status, smoking status, drinking status, physical activity at work and leisure, respectively. As for MS components, nonvegetarians and pescovegetarians had 0.72 (95% CI, 0.62, 0.84), 0.70 (95% CI, 0.57, 0.84) times risk of developing low high density lipoprotein cholesterol (HDL-C), while nonvegetarians had 1.16 (95% CI, 1.02, 1.32) times risk of developing high fasting plasma glucose. Our data suggest that the vegan diets did not decrease the risk of metabolic syndrome compared with pescovegetarian, lactovegetarian and nonvegetarian diets in a Taiwanese cohort.

並列關鍵字

vegan ； pescovegetarian ； lactovegetarian ； nonvegetarian ； metabolic syndrome