Influence of Desflurane on Postoperative Oral Intake Compared with Propofol

地氟醚和异丙酚对术后口腔摄入功能的影响比较

Tomoaki Yatabe ； Koichi Yamashita ； Masataka Yokoyama

《Asia Pacific Journal of Clinical Nutrition》 23卷3期 (2014/09) Pp. 408-412

https://doi.org/10.6133/apjcn.2014.23.3.15

摘要

术后口腔摄入功能是术后早期恢复的一个指征，众所周知麻醉影响术后口腔摄入功能。我们回顾性分析比较了地氟醚麻醉和异丙酚麻醉对早期术后口腔摄入功能的影响。受试者为2013年6月到12月间接受过地氟醚或异丙酚的全麻患者。我们收集分析了147位患者口腔摄入的卡路里和蛋白质总量以及术后（POD）第0、1、2天的恶心呕吐（PONY）的发生情况。地氟醚组（Des）有52名患者，异丙酚（Pro）组有95名患者。在组内PONY在POD第0、1和2天无显著差异。两组间口腔摄入卡路里在POD第0、1和2天的差异不显著（分别是1117±508 vs. 1036±549 kcal/day，p=0.39和1504±368 vs. 1437±433 kcal/day，p=0.35）。两组间口腔蛋白质摄入量在POD第0、1和2天也无显著差异（分别是45.9±21.1 vs. 43.8±22.8 g/day，p=0.60和61.3±15.0 vs. 58.9±18.0 g/day，p=0.42）。本研究表明地氟醚和异丙酚对术后口腔摄入功能的影响相似。此结果还需下一步的前瞻性研究来证实。

關鍵字

术后口服摄入量 ； 术后恶心呕吐 ； 地氟醚 ； 异丙酚 ； 早期恢复

並列摘要

Postoperative oral intake is an important predictor of early postoperative recovery, and anesthesia is known to influence this intake. We compared the influences of desflurane anesthesia and propofol anesthesia on early postoperative oral intake retrospectively. The subjects included a consecutive series of patients who received general anesthesia with propofol or desflurane between June and December 2013. The total amount of calories and proteins taken orally and the incidence of postoperative nausea and vomiting (PONV) on postoperative days (POD) 0, 1, and 2 were collected. A total of 147 patients were analyzed. The desflurane (Des) and the propofol (Pro) groups included 52 and 95 patients, respectively. The incidence of PONV on POD 0, 1, and 2 did not show significant intergroup differences. Total calorie intake on POD 1 and 2 was not significantly different between the 2 groups (1117±508 vs. 1036±549 kcal/day, p=0.39 and 1504±368 vs. 1437±433 kcal/day, p=0.35, respectively). Total amount of protein via oral intake on POD 1 and 2 were not significantly different between the two groups (45.9±21.1 vs. 43.8±22.8 g/day, p=0.60 and 61.3±15.0 vs. 58.9±18.0 g/day, p=0.42, respectively). These findings suggest that desflurane and propofol affect postoperative oral intake in a similar fashion. These results should be confirmed in a future prospective study.

並列關鍵字

postoperative oral intake ； postoperative nausea and vomiting ； desflurane ； propofol ； early recovery